Nocturnal enuresis is when a child, five years of age or older, wets the bed while sleeping at least two times each week. Primary Nocturnal Enuresis describes those children who have always been wet, as opposed to secondary nocturnal enuresis which is defined as a relapse after a child has been completely dry for at least six months. Below you may find medications used to treat or help with Primary Nocturnal Enuresis. More about Primary Nocturnal Enuresis