Flibanserin

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flibanserin

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Flibanserin is a medication intended for the treatment of acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women. It is indicated for women experiencing low sexual desire that causes marked distress or interpersonal difficulty. Flibanserin acts to balance key brain neurotransmitters, specifically targeting serotonin receptors to restore sexual desire rather than working on physical blood flow. Flibanserin 100mg tablets are available to order from our online pharmacy with secure delivery to South Africa.

Table of contents

Generic Flibanserin Buyer and Patient Handbook in South Africa

What is Flibanserin?

Flibanserin is a once-daily oral tablet used to treat low sexual desire that persists for at least six months in pre-menopausal women. It belongs to the class of centrally-acting serotonergic agents and is approved by the South African Health Products Regulatory Authority (SAHPRA). The medication is supplied in a 100 mg pill.

Who Should Use Flibanserin?

  • Pre-menopausal women (generally 18-49 years) with a documented diagnosis of Hypoactive Sexual Desire Disorder (HSDD).
  • Individuals whose low desire is not explained by hormonal, psychiatric, or relationship factors.
  • Patients who are not pregnant, breastfeeding, or planning pregnancy in the near term.

How Does It Work?

Flibanserin modulates brain neurotransmitters by enhancing dopamine and norepinephrine activity while reducing serotonin signaling, which together promote sexual interest. Think of it as adjusting the “engine control” in the brain so desire cues are more readily recognized. The drug does not produce a euphoric high and has no abuse potential in therapeutic doses.

Why Choose Flibanserin?

For women seeking a pharmacologic option specifically approved for low sexual desire, flibanserin offers a targeted mechanism that differs from hormonal therapies. Generic versions provide the same clinical effect as brand-name products at a lower cost, making long-term treatment more affordable. Off-label uses exist, but any alternative purpose should be discussed with a qualified health professional.

Dosage, Administration, Lifestyle and Dietary Recommendations

  • 100 mg taken once daily in the evening.

How to Take

  • Swallow the tablet whole with a full glass of water.
  • Do not crush or split the pill.
  • Take the medication at the same time each night to maintain steady blood levels.

Missed Dose

  • If you remember the missed dose within 12 hours, take it immediately.
  • Skip the dose if more than 12 hours have passed and resume the regular schedule at bedtime.

Overdose

  • If an overdose is suspected, seek urgent medical attention or call the local poison information centre (180 721 200).
  • Provide details of the amount taken and the time of ingestion.

Special Populations

  • Elderly: No dose reduction is required, but monitor for increased Sedation.
  • Renal or hepatic impairment: Use with caution; dose adjustment is not routinely recommended but clinical judgment is essential.
  • Women of child-bearing potential: Use effective contraception, as safety in pregnancy has not been established.

Lifestyle & Diet

  • Avoid alcohol while taking flibanserin; concurrent use can cause severe hypotension and syncope.
  • Grapefruit juice does not significantly affect flibanserin levels, but large amounts of fatty meals may delay absorption.
  • Maintain a balanced diet and regular exercise to support overall sexual health.

Precautions and Warnings

  • Do not consume alcohol within three hours before or after the dose.
  • Report any episodes of dizziness, fainting, or sudden drops in blood pressure.
  • Use caution when operating machinery or driving until you know how the medication affects you.

Drug Interactions

Drug Class Risk Action
Strong CYP3A4 inhibitors (e.g., ketoconazole) ↑ flibanserin levels → sedation, hypotension Avoid concurrent use
CNS depressants (e.g., benzodiazepines) Additive sedation Monitor closely
Antidepressants that increase serotonin (e.g., SSRIs) Potential serotonin imbalance Review necessity; consider alternatives

Potential Side Effects

Common Side Effects

  • Dizziness
  • Nausea
  • Sleepiness or Fatigue
  • Dry mouth

Less Common Side Effects

Serious Side Effects

  • Severe hypotension or fainting (especially with alcohol) - seek medical help immediately.
  • Persistent Depression or mood changes - contact a health professional promptly.

Who Should Avoid This Medication?

  • Women who are pregnant, planning pregnancy, or breastfeeding.
  • Individuals with uncontrolled hypertension or a history of severe hypotension.
  • Patients currently taking strong CYP3A4 inhibitors or who cannot abstain from alcohol.

Storage Instructions

  • Keep the tablets in their original blister pack.
  • Store at 15 °C-30 °C (59 °F-86 °F) away from direct sunlight.
  • Keep out of reach of children and pets.

Flibanserin Alternatives

Name Class Key Difference
Bremelanotide (intranasal) Peptide agonist On-demand dosing; not for daily use
Testosterone gel (topical) Hormone therapy May increase libido in both men and women
Placebo/psychotherapy Non-pharmacologic Addresses psychological contributors

Frequently Asked Questions

How long does it take to notice an improvement?

Most women report a gradual increase in desire after four to eight weeks of consistent daily use.

Can I take flibanserin with birth control pills?

Yes, there is no known interaction with hormonal contraceptives, but maintain regular contraceptive use to avoid pregnancy.

What should I do if I feel dizzy after my dose?

Sit or lie down immediately, avoid standing quickly, and refrain from drinking alcohol. If dizziness persists, consult a health professional.

Is it safe to drive after taking flibanserin?

Start the medication at night to gauge its sedative effect. Until you know how it affects you, avoid driving or operating heavy machinery.

Can men use flibanserin for low libido?

Flibanserin is not approved for use in men, and its safety and efficacy have not been studied in this population.

What happens if I accidentally take two pills at once?

An accidental double dose may increase the risk of dizziness and low blood pressure. Seek medical advice promptly.

Does flibanserin affect menstrual cycles?

No direct effect on the menstrual cycle has been reported, but any unusual bleeding should be evaluated.

Will I need regular blood tests while on flibanserin?

Routine laboratory monitoring is not required unless you have underlying liver or kidney disease.

Glossary

  • Hypoactive Sexual Desire Disorder (HSDD): Persistent lack of sexual desire causing personal distress.
  • CYP3A4: An enzyme in the liver that metabolises many drugs; inhibitors can raise medication levels.
  • Serotonin: A brain chemical that influences mood, sleep, and sexual function; excessive activity can reduce desire.

Disclaimer

The information provided here is for general educational purposes only and reflects current knowledge about flibanserin. It does not constitute medical advice, and off-label uses should be discussed with a qualified health professional. Our online platform offers convenient access to approved medicines, but the ultimate responsibility for safe and appropriate use rests with the individual. Always consult a health professional before starting, stopping, or changing any medication regimen.

Flibanserin Properties

  • Conditions To Treat: Hypoactive sexual desire disorder
  • Clinical Use: Treatment of low sex drive in premenopausal women
  • Spectrum Of Activity: Serotonin receptor agonist/antagonist
  • Mechanism Of Action: Increases dopamine and norepinephrine and decreases serotonin, leading to an increase in sexual desire
  • Length Of Use: Daily use for up to 8 weeks
  • Recommended Dosage: 100mg per day at bedtime
  • Side Effects: Drowsiness, dizziness, fatigue, nausea, low blood pressure

Flibanserin Drug Class

Miscellaneous Central Nervous System Agents

Flibanserin Connected Conditions

How to Purchase Flibanserin Through Our Online Pharmacy

Buying Flibanserin from our online pharmacy is simple and convenient. Start by selecting the desired dosage and quantity displayed on the product page. The price updates in real-time, so you know exactly what to expect before proceeding. Click the Add to Basket button to include your selection in your cart. You can continue browsing for additional medications or proceed directly to the checkout. On the Checkout Page, finalize your purchase using our secure payment system, ensuring your details remain confidential and protected.

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