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Astelin (Azelastine) Buyer and Patient Handbook in South Africa

What is Astelin?

Astelin is a nasal spray containing the antihistamine azelastine, used to treat Allergic Rhinitis. It belongs to the intranasal antihistamine class and relieves sneezing, itching, and runny nose caused by hay fever or other allergens. Astelin is approved by the South African Health Products Regulatory Authority (SAHPRA) and is supplied in a 10 ml sprayer.

Who Should Use Astelin?

• Adults and adolescents (12 years and older) with seasonal or perennial allergic rhinitis.
• Individuals seeking non-sedating relief from nasal allergy symptoms.
• Patients who prefer a locally available nasal spray rather than oral antihistamines.

How Does It Work?

Astelin works by blocking histamine H1 receptors in the nasal mucosa, preventing the cascade that leads to irritation and mucus production. Think of it as putting a “stop sign” on the road where allergy chemicals travel, so they can’t trigger the usual sneezing and runny-nose response. It has a low potential for abuse and is not a controlled substance.

Why Choose Astelin?

Astelin offers rapid, targeted relief without the systemic Drowsiness commonly associated with oral antihistamines. As a brand-name product, it provides consistent dosing and spray performance; generic azelastine alternatives are also available for cost-conscious patients.

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

• Adults and adolescents (≥12 years): 1-2 sprays per nostril twice daily (morning and evening).
• Maximum: 4 sprays per nostril per day.

How to Take

1. Gently blow your nose to clear the passages.
2. Shake the bottle for a few seconds.
3. Insert the tip into one nostril, close the other nostril with a finger, and press down to release the spray while breathing in gently.
4. Repeat in the other nostril.

Missed Dose

If you miss a dose, take it as soon as you remember unless it is close to the time of your next scheduled dose; do not double-dose.

Overdose

In case of accidental overdose, contact emergency services (112) or a local poison information centre. Symptoms may include excessive drowsiness or severe nasal irritation.

Special Populations

• Elderly: No dosage adjustment needed, but monitor for increased drowsiness.
• Children under 12 years: Not approved in South Africa; consult a healthcare professional for alternatives.
• Renal or hepatic impairment: No specific dose change required, but use caution and monitor.

Lifestyle & Diet

• Avoid using more than the recommended amount, as excess can cause irritation.
• No known food interactions, but limit concurrent use of other nasal decongestants to reduce risk of rebound congestion.

Precautions and Warnings

• Do not use if you have a known allergy to azelastine or any excipients in the sprayer.
• Inform your pharmacist if you are pregnant, planning a pregnancy, or breastfeeding.
• Use the spray only for the indicated condition; persistent symptoms may require further evaluation.

Drug Interactions

Potential Side Effects

Common Side Effects

• Bitter or metallic taste
• Mild nasal irritation or burning
• Drowsiness (less common than with oral antihistamines)

Less Common Side Effects

• Headache
• Sneezing shortly after administration
• Dry mouth

Serious Side Effects

• Severe allergic reaction (rash, swelling, difficulty breathing) - seek immediate medical help
• Persistent nasal bleeding - consult a healthcare professional

Who Should Avoid This Medication?

• Individuals with hypersensitivity to azelastine or any component of the formulation.
• Patients currently experiencing a severe nasal infection.
• Children under 12 years of age (not approved).

Storage Instructions

• Keep the bottle at room temperature (15 °C - 30 °C).
• Store away from direct sunlight and heat sources.
• Keep out of reach of children; the spray nozzle should be capped after each use.

Astelin Alternatives

Frequently Asked Questions

How quickly will I feel relief after the first spray?

Most users notice a reduction in sneezing and nasal itching within 15-30 minutes of the first dose.

Can I use Astelin while I’m pregnant?

Astelin is classified as Category B2 in South Africa, indicating no proven risk, but you should discuss use with your healthcare provider.

Is it safe to use Astelin together with a nasal decongestant?

Yes, but limit combined use to three consecutive days to avoid rebound congestion.

What should I do if I accidentally spray more than the recommended dose?

If you experience significant irritation or drowsiness, contact a pharmacist or medical professional for guidance.

Can I use Astelin with other allergy medicines like oral antihistamines?

You can, but it may increase the risk of drowsiness; monitor how you feel and adjust if necessary.

Does Astelin have any effect on my sense of smell?

Typically it does not impair smell, and many users report improved nasal patency, which can enhance smelling ability.

How long can I safely use Astelin?

Astelin is safe for long-term daily use under medical supervision; regular review with a healthcare professional is advisable.

Will Astelin cause me to feel sleepy at work?

Drowsiness is uncommon but can occur in sensitive individuals; if it affects your performance, consider using the evening dose earlier.

Glossary

• Antihistamine: A drug that blocks histamine receptors to reduce allergy symptoms.
• Mast cell stabilizer: A substance that prevents mast cells from releasing histamine.
• Rebound congestion: Worsening nasal blockage after stopping a decongestant spray.

Disclaimer

The information provided here is for general educational purposes only and does not replace professional medical advice. Always consult a qualified healthcare practitioner before starting, stopping, or changing any medication. This article does not endorse off-label use; any such use should be discussed with a clinician. Our online pharmacy service offers convenient access to approved medicines, but responsibility for safe use rests with the patient.