Buy Prednisolone Online

Generic Prednisolone Buyer and Patient Handbook in South Africa

What is Prednisolone?

Prednisolone is a synthetic corticosteroid used to reduce inflammation and suppress an over-active immune response. It belongs to the glucocorticoid class and is commonly prescribed for Allergic Reactions, Asthma exacerbations, autoimmune disorders, and certain skin conditions. In South Africa, prednisolone is approved by the South African Health Products Regulatory Authority (SAHPRA) and is available as oral tablets in strengths of 5 mg, 10 mg, 20 mg and 40 mg.

Who Should Use Prednisolone?

• Adults experiencing moderate to severe asthma attacks.
• Patients with allergic dermatitis, Urticaria, or severe Allergic Rhinitis.
• Individuals diagnosed with autoimmune diseases such as Rheumatoid Arthritis or Systemic Lupus Erythematosus.
• People needing short-term anti-inflammatory therapy after surgery or trauma.

How Does It Work?

Prednisolone mimics the natural hormone cortisol, binding to glucocorticoid receptors in cells and altering gene expression. This reduces the production of inflammatory chemicals such as prostaglandins and cytokines. The net effect is less swelling, redness, and immune-mediated damage. It works quickly, often within a few hours, making it useful for acute flare-ups.

Why Choose Prednisolone?

• Cost-effective: As a generic, it is substantially cheaper than brand-name corticosteroids while offering the same therapeutic effect.
• Broad utility: Effective for a wide range of inflammatory and allergic conditions, allowing one medication to address multiple symptoms.
• Flexible dosing: Available in several tablet strengths, facilitating precise dose adjustments. Off-label uses exist (e.g., certain eye inflammations) but should be discussed with a qualified health professional.

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

• 5 mg - mild inflammation or maintenance therapy.
• 10 mg - moderate symptoms or initial control.
• 20 mg - acute exacerbations (e.g., asthma attack).
• 40 mg - severe flare-ups; usually short-term.

Dosage is individualized; follow the prescribing information or a health-care professional’s guidance.

How to Take

1. Swallow the tablet whole with a full glass of water.
2. Take with food or a light snack to minimise stomach irritation.
3. Do not crush or chew unless instructed otherwise.

Missed Dose

• If you remember within 12 hours, take it as soon as possible.
• If it’s longer than 12 hours, skip the missed dose and continue with the next scheduled dose. Do not double-dose.

Overdose

• Seek emergency medical help if you experience severe nausea, vomiting, confusion, or rapid heartbeat.
• Contact your local poison information centre (e.g., 080 110 555).

Special Populations

• Elderly: Start with the lowest effective dose; monitor for bone loss and blood sugar changes.
• Children: Use pediatric formulations or dose by weight; not covered in this adult-focused guide.
• Kidney or liver impairment: Dose reduction may be required; consult a health professional.

Lifestyle & Diet

• Avoid abrupt cessation; taper under guidance to prevent adrenal insufficiency.
• Limit high-sugar foods if you have Diabetes, as prednisolone can raise blood glucose.
• Grapefruit juice can increase prednisolone levels - avoid or discuss with a health professional.

Precautions and Warnings

• Do not use for viral infections such as flu or COVID-19 without medical direction.
• Long-term use may lead to bone loss, cataracts, High Blood Pressure, and increased infection risk.
• Monitor blood pressure, blood sugar, and weight regularly during extended therapy.

Drug Interactions

Potential Side Effects

Common Side Effects

• Increased appetite
• Mild Insomnia
• Upset stomach or indigestion

Less Common Side Effects

• Mood swings or irritability
• Acne or skin thinning
• Fluid retention leading to swelling

Serious Side Effects

• Severe allergic reaction (rash, swelling, difficulty breathing) - seek immediate medical help.
• Uncontrolled high blood sugar - contact a health professional.
• Signs of infection (fever, persistent Cough) - notify a health professional promptly.

Who Should Avoid This Medication?

• Patients with uncontrolled fungal, bacterial or viral infections.
• Individuals with known hypersensitivity to prednisolone or any tablet excipients.
• Those with active peptic ulcer disease unless benefits outweigh risks.

Storage Instructions

• Keep tablets in the original container, tightly closed.
• Store at 20-25 °C (68-77 °F); protect from moisture and direct sunlight.
• Keep out of reach of children and pets.

Prednisolone Alternatives

Frequently Asked Questions

How quickly can I expect relief after the first dose?

Most people notice a reduction in swelling or breathing difficulty within 4-6 hours, though full effect may take a day.

Can I drink alcohol while taking prednisolone?

Occasional moderate alcohol is generally safe, but heavy drinking can increase stomach irritation and infection risk.

Will prednisolone affect my mood?

Some users report mood changes such as irritability or mild Anxiety, especially at higher doses.

Is it safe to use prednisolone during pregnancy?

Prednisolone is classified as Category C in South Africa; it should only be used if the potential benefit justifies the risk. Discuss with a health professional.

How long should a typical course last?

Short courses for asthma or allergy flare-ups often range from 5 to 14 days. Longer courses are individualized.

Can I stop the medication abruptly after a few weeks?

Abrupt cessation after more than a few weeks can cause adrenal insufficiency; a tapering schedule is recommended.

Does prednisolone cause weight gain?

It can increase appetite and fluid retention, potentially leading to modest weight gain.

What should I do if I develop a skin rash?

Stop the medication and seek medical advice promptly; a rash may indicate an allergic reaction.

Are there any foods I must avoid?

Grapefruit juice may raise drug levels; limit or avoid it.

How does prednisolone differ from over-the-counter antihistamines?

Prednisolone suppresses the immune response and inflammation, while antihistamines block histamine receptors to alleviate allergy symptoms.

Glossary

• Glucocorticoid: A class of steroid hormones that reduce inflammation and modulate the immune system.
• Adrenal insufficiency: A condition where the body cannot produce adequate cortisol, potentially triggered by sudden steroid withdrawal.
• Tapering: Gradually reducing the medication dose to allow the body’s natural hormone production to resume.

Disclaimer

The information provided here is for general educational purposes only and does not replace professional medical advice. Use of prednisolone for any off-label indication should be discussed with a qualified health professional. This guide reflects the policies of our online pharmacy platform in South Africa; readers are responsible for ensuring the medication is appropriate for their personal health needs. Always consult a qualified health professional before starting, stopping, or changing any medication regimen.