Buy Zenegra Online

Zenegra (Sildenafil) Buyer and Patient Handbook in South Africa

What is Zenegra?

Zenegra is a tablet-form medication containing the active ingredient sildenafil, used to treat Erectile Dysfunction in men. It belongs to the phosphodiesterase-5 (PDE5) inhibitor class and is approved by the South African Health Products Regulatory Authority (SAHPRA). The tablets are available in 50 mg and 100 mg strengths.

Who Should Use Zenegra?

• Adult men diagnosed with erectile dysfunction.
• Individuals seeking an on-demand solution rather than daily therapy.
• Patients who have stable cardiovascular status and are not taking contraindicated nitrate medications.

How Does It Work?

Sildenafil blocks the enzyme PDE5, which normally breaks down cyclic guanosine monophosphate (cGMP) in the penis. By preserving cGMP, blood vessels relax and blood flow increases during sexual stimulation, allowing an erection to occur. The effect relies on sexual arousal; the drug alone does not cause an erection.

Why Choose Zenegra?

Zenegra offers a cost-effective generic option with the same clinical efficacy as branded sildenafil products. It provides rapid onset (≈30-60 minutes) and a reliable duration of action (up to 4-5 hours). Off-label uses, such as pulmonary arterial hypertension, should only be considered under professional guidance.

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

• Start with 50 mg taken about one hour before sexual activity.
• If tolerated and not effective, increase to 100 mg. Do not exceed one dose per 24 hours.

How to Take

• Swallow the tablet whole with a glass of water.
• It can be taken with or without food; a high-fat meal may delay onset.

Missed Dose

• If you forget a dose and still have sexual activity planned within 4 hours, take the missed tablet.
• If more than 4 hours have passed, skip the dose and resume the regular schedule.

Overdose

• Seek immediate medical attention if you experience severe dizziness, chest Pain, or a prolonged erection lasting over 4 hours.

Special Populations

• Elderly: Start with 50 mg; monitor blood pressure.
• Renal or hepatic impairment: Use the lowest effective dose and consult a health professional.
• Children and adolescents: Not licensed; avoid use.

Lifestyle & Diet

• Avoid grapefruit juice as it can increase sildenafil levels.
• Moderate alcohol intake; excessive drinking may reduce effectiveness.
• Maintain a healthy weight and regular exercise to support overall sexual health.

Precautions and Warnings

• Do not use if you are taking nitrate medication (e.g., nitroglycerin) or have a known hypersensitivity to sildenafil.
• Caution in men with severe cardiovascular disease, uncontrolled hypertension, or recent stroke.
• Notify a health professional if you experience sudden vision loss, hearing changes, or prolonged erections.

Drug Interactions

Potential Side Effects

Common Side Effects

• Headache
• Flushing
• Indigestion
• Nasal congestion
• Visual colour changes

Less Common Side Effects

• Dizziness
• Back pain
• Nausea

Serious Side Effects

• Chest pain or irregular heartbeat - call emergency services
• Prolonged erection (priapism) - seek urgent medical care
• Sudden vision or hearing loss - consult a doctor immediately

Who Should Avoid This Medication?

• Patients on nitrate therapy
• Men with severe Heart Failure or recent myocardial infarction
• Individuals with known allergic reaction to sildenafil or any tablet excipients
• Those with uncontrolled low blood pressure

Storage Instructions

• Keep the tablets in the original blister pack.
• Store at room temperature (15-30 °C) away from moisture and direct sunlight.
• Keep out of reach of children and pets.

Zenegra Alternatives

Frequently Asked Questions

How quickly does Zenegra start working?

Zenegra typically begins to work within 30-60 minutes after ingestion.

Can I drink alcohol while taking Zenegra?

Moderate alcohol is acceptable, but excessive drinking may reduce the drug’s effectiveness.

Is Zenegra safe for men with high blood pressure?

It can be used if blood pressure is well-controlled; uncontrolled hypertension requires medical review.

Can I take Zenegra every day?

Zenegra is intended for on-demand use; daily dosing is not recommended without professional advice.

What should I do if I miss a dose?

If sexual activity is still planned within 4 hours, take the missed tablet; otherwise, skip it and continue as usual.

Does grapefruit juice affect Zenegra?

Yes, grapefruit can increase sildenafil levels, potentially heightening side effects; avoid it.

Will Zenegra affect my fertility?

There is no evidence that sildenafil impacts sperm production or fertility.

Do I need to fast before taking Zenegra?

Fasting is not required, though a heavy fatty meal may delay onset.

Can I combine Zenegra with another erectile dysfunction medication?

Do not combine with other PDE5 inhibitors; this can cause serious adverse effects.

What is the safest way to handle a prolonged erection?

If an erection lasts more than 4 hours, seek immediate medical attention to prevent tissue damage.

Glossary

• PDE5 inhibitor: A drug that blocks phosphodiesterase-5, enhancing blood flow to the penis.
• cGMP: A messenger molecule that relaxes smooth muscle, allowing erection when sexual stimulation occurs.
• Half-life: The time required for the drug’s plasma concentration to reduce by half; sildenafil’s half-life is about 4 hours.

Disclaimer

The information provided here is for general educational purposes only and does not replace professional medical advice. Off-label uses, dosing adjustments, and safety concerns should be discussed with a qualified health professional. Our online pharmacy service offers convenient access to approved medicines; users remain responsible for compliance with local regulations and for consulting a doctor before starting any new medication.