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Aterax (Hydroxyzine) Buyer and Patient Handbook - South Africa

What is Aterax?

Aterax is an oral antihistamine belonging to the first-generation H₁-receptor antagonists. It is used to relieve itching, hives, allergic skin reactions, and to provide short-term relief of Anxiety or tension. The product is authorized by the South African Health Products Regulatory Authority (SAHPRA) and is supplied as a tablet in strengths of 10 mg and 25 mg.

Who Should Use Aterax?

• Adults and adolescents (≥12 years) experiencing moderate to severe allergic skin symptoms.
• Patients who need occasional Sedation for anxiety-related tension.
• Individuals who have no known hypersensitivity to hydroxyzine or any tablet excipients.

How Does It Work?

Aterax blocks histamine-H₁ receptors in the skin, blood vessels, and brain. By preventing histamine from binding, it stops the cascade that leads to itching, swelling, and redness. The same receptor blockade in the central nervous system produces a calming effect, which can help reduce anxiety or aid sleep when required. Caution: because it can cause Drowsiness, avoid operating heavy machinery or driving until you know how the medication affects you.

Why Choose Aterax?

• Proven efficacy: Hydroxyzine has been used for decades with a well-documented safety profile.
• Two dose options: The 10 mg tablet is suitable for mild symptoms, while 25 mg provides stronger relief for severe reactions.
• Cost-effective: As a generic product, Aterax offers the same therapeutic benefit as branded antihistamines at a lower price point.

Off-label use (e.g., chronic Insomnia) should only be considered after consulting a qualified health professional.

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

• Adults (≥18 years): 10 mg up to three times daily or 25 mg once daily as needed.
• Adolescents (12-17 years): 10 mg up to three times daily.

How to Take

. Swallow the tablet whole with a full glass of water.

2. Can be taken with or without food; food may lessen mild stomach irritation.

Missed Dose

If you forget a dose, take it as soon as you remember unless it is near the time of the next scheduled dose. Do not double-dose.

Overdose

In case of suspected overdose, seek emergency medical help immediately. Symptoms may include extreme drowsiness, rapid heart rate, or low blood pressure.

Special Populations

• Elderly: Start with the lowest dose (10 mg) and monitor for excessive sedation.
• Renal impairment: Reduce dose by 50 % if creatinine clearance is <30 mL/min.
• Pregnancy & lactation: Use only if clearly needed; discuss risks with your clinician.

Lifestyle & Diet

• Avoid alcohol and other central nervous system depressants while taking Aterax, as they can intensify drowsiness.
• No significant food interactions, but grapefruit juice may increase plasma levels-use with caution.

Precautions and Warnings

• Do not operate vehicles or machinery until you know how Aterax affects you.
• Use caution if you have Glaucoma, enlarged prostate, or severe constipation, as anticholinergic effects may worsen these conditions.
• Discontinue use and seek medical advice if you develop a rash, fever, or difficulty breathing.

Drug Interactions

Potential Side Effects

Common Side Effects

• Drowsiness or Fatigue
• Dry mouth
• Headache

Less Common Side Effects

• Blurred vision
• Constipation
• Dizziness

Serious Side Effects

• Severe skin rash or hives (possible allergic reaction)
• Rapid heartbeat or palpitations
• Difficulty urinating or bladder retention

If any serious symptom appears, contact a health professional immediately.

Who Should Avoid This Medication?

• Known hypersensitivity to hydroxyzine or any tablet component.
• Patients with a history of severe arrhythmias.
• Individuals taking monoamine oxidase inhibitors within the past 14 days.

Storage Instructions

• Keep the tablets in their original container, tightly closed.
• Store at 15 °C - 30 °C; protect from moisture and direct sunlight.
• Keep out of reach of children and pets.

Aterax Alternatives

Frequently Asked Questions

How quickly does Aterax start working?

Aterax usually begins to relieve itching and reduce anxiety within 30 minutes after oral intake.

Can I take Aterax every day for chronic allergies?

It is intended for short-term or as-needed use. For chronic conditions, discuss long-term management with a health professional.

Will Aterax make me sleepy at work?

Drowsiness is common, especially at higher doses. If you need to stay alert, start with the lowest dose and assess how you feel before resuming work tasks.

Is it safe to combine Aterax with my regular asthma inhaler?

There is no direct interaction with most inhaled bronchodilators, but always confirm with your clinician.

Can I drink coffee while taking Aterax?

Caffeine does not affect Aterax’s efficacy, but excessive caffeine may counteract the sedative effect you might need.

What should I do if I miss a dose before bedtime?

Take the missed dose if you have at least 4 hours before your usual bedtime; otherwise, skip it and resume your regular schedule.

Is Aterax suitable for children under 12?

Safety and efficacy have not been established for children younger than 12 years; consult a pediatric specialist for alternatives.

How often can I use the 25 mg tablet?

The 25 mg tablet is intended as a once-daily dose for severe symptoms; do not exceed this frequency.

Does Aterax interact with HIV medication?

No major interactions are reported, but always review all current medicines with a pharmacist or clinician.

Can I take Aterax during a road trip?

Only if you are certain it will not impair your alertness. Test the effect on a short drive first.

Glossary

• Antihistamine: A drug that blocks the action of histamine, reducing allergy symptoms.
• First-generation: An older class of antihistamines that cross the blood-brain barrier, often causing drowsiness.
• Anticholinergic: Effects that reduce secretions and smooth-muscle activity; can cause dry mouth and constipation.

Disclaimer

The information provided here is for general educational purposes and does not replace professional medical advice. Off-label use should only be considered after discussing potential risks and benefits with a qualified health professional. This handbook reflects current knowledge about Aterax (hydroxyzine) as of the publication date. Readers are responsible for verifying the relevance of the content to their personal health situation and for consulting a clinician before initiating or changing any medication regimen. Our service facilitates access to approved medicines in South Africa, but we do not dispense, prescribe, or guarantee clinical outcomes.