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Singulair (Montelukast) Buyer and Patient Handbook in South Africa

What is Singulair?

Singulair is a leukotriene receptor antagonist used to treat Asthma and Allergic Rhinitis. It belongs to the allergy-asthma drug class and is approved by the South African Health Products Regulatory Authority (SAHPRA). The medication is supplied as an oral pill in 4 mg, 5 mg, and 10 mg strengths.

Who Should Use Singulair?

• Adults and children ≥ 12 months with persistent asthma.
• Individuals with seasonal or perennial allergic rhinitis.
• Patients who need an add-on therapy to inhaled corticosteroids.

How Does It Work?

Singulair blocks leukotrienes, inflammatory chemicals that cause airway narrowing and mucus production. By preventing leukotriene binding, the drug helps keep the airways open, reducing wheezing, coughing, and nasal congestion. It does not have a potential for abuse and is safe when taken as directed.

Why Choose Singulair?

• Convenient once-daily dosing simplifies treatment routines.
• Proven efficacy in both asthma control and allergy symptom relief.
• Generic montelukast tablets are widely available, offering a cost-effective alternative to brand-only options.

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

How to Take

• Swallow the tablet whole with a glass of water.
• Take it at the same time each day, preferably in the evening.
• Food does not affect absorption, so it can be taken with or without meals.

Missed Dose

If you remember the missed dose within 12 hours, take it now. If it is later than 12 hours, skip it and resume the regular schedule-do not double-dose.

Overdose

If an overdose is suspected, seek urgent medical attention or contact the Poisons Information Centre (080 567 567). Provide details of the amount taken and the time of ingestion.

Special Populations

• Elderly: No dose adjustment needed; monitor for dizziness.
• Renal or hepatic impairment: No specific modification required, but clinical judgement is advised.
• Pregnancy & breastfeeding: Generally considered safe, but discuss with a healthcare professional.

Lifestyle & Diet

• Grapefruit juice does not interact with Singulair.
• Alcohol consumption does not affect its efficacy, but excessive drinking may worsen asthma symptoms.
• Maintain regular exercise; the medication does not impair physical performance.

Precautions and Warnings

• Use only for the conditions listed; do not self-treat other illnesses.
• Inform your clinician of any liver disease, immune disorders, or previous hypersensitivity reactions.
• Monitor for changes in mood or behavior, especially in children; report unusual symptoms promptly.

Drug Interactions

Potential Side Effects

Common Side Effects

• Headache
• Stomach Pain or indigestion
• Nasal congestion

Less Common Side Effects

• Dizziness
• Fatigue
• Diarrhoea

Serious Side Effects

• Severe allergic reaction (rash, swelling, difficulty breathing) - seek immediate medical help.
• Mood changes, Depression, or suicidal thoughts - contact a healthcare provider right away.

Who Should Avoid This Medication?

• Anyone with a known hypersensitivity to montelukast or any component of the tablet.
• Patients with active liver disease requiring close monitoring.

Storage Instructions

• Keep below 30 °C (86 °F); avoid direct sunlight.
• Store in a dry place, out of reach of children.
• Do not use tablets that are discoloured or broken.

Singulair Alternatives

Frequently Asked Questions

How soon can I expect relief after starting Singulair?

Most patients notice improvement in asthma symptoms within 2-3 days; allergy relief may take up to a week.

Can I use Singulair with my inhaler?

Yes, Singulair can be taken alongside inhaled corticosteroids or bronchodilators as part of a combined asthma regimen.

Is it safe to take Singulair during a cold?

The medication can be continued during mild upper-respiratory infections, but discuss any worsening symptoms with a clinician.

Do I need to take Singulair every day even when I feel fine?

For chronic asthma, daily use maintains control and prevents flare-ups, even when symptoms are absent.

Can I crush the tablet if I have difficulty swallowing?

Do not crush or chew; swallow the tablet whole to ensure proper absorption.

What should I do if I develop a rash?

Stop the medication and seek medical evaluation promptly.

Does Singulair affect blood pressure?

No significant effect on blood pressure has been reported.

Can I travel abroad with Singulair?

Yes, but keep the medication in its original packaging with a copy of the prescription label for customs checks.

Glossary

• Leukotriene: An inflammatory mediator that narrows airways and promotes mucus production.
• Receptor antagonist: A drug that blocks a specific receptor, preventing a natural substance from binding.
• Bioequivalence: When two drug products release the same amount of active ingredient into the bloodstream.

Disclaimer

This handbook provides general information only and does not replace professional medical advice. Off-label use should be discussed with a qualified healthcare professional. Readers are responsible for verifying the suitability of Singulair for their personal health needs. Our service offers information about medication availability and ordering through a regulated South African pharmacy, but we do not dispense prescriptions. Always consult a doctor or pharmacist before starting or changing any medication.