Skip to content

Multiple Sclerosis-associated Fatigue

Multiple sclerosis-associated fatigue is a persistent, invisible tiredness caused directly by the condition itself. It differs sharply from the exhaustion anyone feels after a long day, and it is a major cause of people stopping work or reducing their hours.

Key points

  • Primary ms fatigue arises from the condition’s effect on the nervous system, whereas secondary fatigue can follow disrupted sleep, medication effects or reduced activity.
  • Because the symptom is invisible, others may not recognise its severity, adding a layer of frustration to the physical exhaustion.

Medicines listed for Multiple Sclerosis-associated Fatigue

The single product listed for this condition is Naltrexone in a 1.5 mg capsule. This dose is well below the amount used in addiction treatment. Low dose naltrexone is studied in the context of autoimmune and neurological conditions such as multiple sclerosis.

Further reading