Menopause & HRT
Oestrogen and progestogen tablets for menopause symptoms, hormone replacement and other related hormone conditions make up this small range, including Estrace, Duphaston, Provera and Tibofem.

Progesterone Capsules
200mg
Progesterone capsules for missed periods and endometrial hyperplasia. They deliver the same hormone the body makes, helping to regulate the menstrual cycle.
Key points
- Combined HRT contains oestrogen and a progestogen, while oestrogen-only HRT does not.
- HRT comes in several forms, including tablets, patches, gels and local vaginal preparations.
- Provera, Duphaston and Progesterone Capsules are progestogen medicines listed for amenorrhoea, uterine bleeding or related hormone conditions rather than menopause symptoms directly.
- Estrace and Tibofem, by contrast, are listed for menopausal vasomotor symptoms and postmenopausal osteoporosis.
Estrace and Tibofem for menopausal symptoms
Estradiol is the ingredient in Estrace, listed for menopausal vasomotor symptoms, atrophic vaginitis and postmenopausal osteoporosis. Tibofem contains tibolone, listed for the same vasomotor symptoms and postmenopausal osteoporosis.
Provera, Duphaston and Progesterone Capsules for other hormone conditions
Medroxyprogesterone acetate is the ingredient in Provera, listed for secondary amenorrhoea, abnormal uterine bleeding and endometrial hyperplasia. Progesterone itself, in Progesterone Capsules, is listed for secondary amenorrhoea and endometrial hyperplasia. Duphaston contains dydrogesterone, listed for progesterone deficiency, endometriosis and threatened miscarriage.
Further reading
Which menopause and HRT medicines are available on Direct Meds?
Direct Meds lists 5 menopause and HRT medicines. Together they contain 5 different active ingredients, including estradiol, dydrogesterone and progesterone. Examples include Estrace and Duphaston; all 5 medicines are listed on this page.
Can I buy estradiol tablets in South Africa?
Yes. Estradiol tablets on Direct Meds include Estrace (estradiol).
What are menopause and HRT medicines used for?
Between them, the menopause and HRT medicines on Direct Meds are used for menopausal vasomotor symptoms, postmenopausal osteoporosis, secondary amenorrhoea, endometrial hyperplasia and atrophic vaginitis.
In what forms are menopause and HRT medicines sold?
Mostly as tablets, with some capsules. The forms and strengths are listed on each product page.
How do I choose between the menopause and HRT medicines on Direct Meds?
Start with the active ingredient: there are 5 different ones in this range. Products with the same active ingredient contain the same medicine. Compare their strength, form and price per unit. Each product page's details table lists uses, how quickly it works, side effects and interactions. If you take other medicines, are pregnant or have a long-term condition, check with a doctor or pharmacist first.
Will I receive branded or generic menopause and HRT medicines?
Usually a generic. Names such as Estrace and Duphaston identify the medicine: you receive a generic with the same active ingredient and strength. Another medicine, Tibofem, is listed under its own name; for it you receive a branded generic or generic with the same active ingredient, depending on stock.
What you will receive →How much do menopause and HRT medicines cost in South Africa?
Compare each medicine, strength and pack on its product page. Prices are shown in rand, converted from US dollars, so the final rand total can change with the exchange rate. Larger packs usually cost less per unit.
Payment and prices →Do I need a prescription to buy menopause and HRT medicines in South Africa?
No. Direct Meds does not ask for a prescription to order menopause and HRT medicines. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Can I order menopause and HRT medicines online in South Africa?
Yes. Choose a product, strength and pack, then check out. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →


