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Weight ManagementWeight Management

Mysimba and Xenical carry a stated weight-management indication in this range, while Rybelsus, Victoza and Clenbuterol Tablets are attached here for diabetes or respiratory reasons instead.

Rybelsus

Semaglutide

3mg · 7mg · 14mg

Semaglutide tablets for type 2 diabetes. It mimics a gut hormone to release more insulin and slow stomach emptying.

From$14.67/ tabletView

Mysimba

Naltrexone, Bupropion

90mg + 8mg

Naltrexone and bupropion tablets for weight management. They work on the brain's reward system to cut food cravings.

From$2.89/ tabletView

Xenical

Orlistat

60mg · 120mg

Orlistat capsules for obesity management. It stops some dietary fat from being absorbed in the gut.

From$1.06/ capsuleView

Victoza

Liraglutide

6mg

Liraglutide auto-injector for type 2 diabetes. It helps the body release insulin when blood sugar rises.

From$401.50/ auto-injectorView

Clenbuterol Tablets

Clenbuterol

40mcg

Clenbuterol tablets for bronchospasm and COPD. It is not a steroid, despite being used for weight loss in some countries, and it can cause a rapid heartbeat.

From$2.04/ tabletView

Key points

  • Weight management is a long-term process that can involve different levels of support, not medicine alone.
  • Clinical assessment looks at weight-related health conditions and other factors that can affect a person’s weight.
  • Medicine, when used, sits within a broader, reviewed weight-management plan rather than standing alone.
  • Mysimba is a tablet combining naltrexone with bupropion, while Xenical is a capsule containing orlistat alone.

Naltrexone, bupropion and orlistat

Naltrexone is combined with bupropion in Mysimba, listed for chronic weight management. Xenical contains orlistat, an anti-obesity agent listed for obesity management.

Diabetes and respiratory medicines also attached here

Semaglutide is the ingredient in Rybelsus, and liraglutide is the ingredient in Victoza, both listed for type 2 diabetes mellitus. Clenbuterol Tablets contains clenbuterol, listed for bronchospasm and chronic obstructive pulmonary disease.

Further reading

What weight loss medicines does Direct Meds sell?

Direct Meds lists 5 weight loss medicines. Together they contain 6 different active ingredients, including semaglutide, naltrexone and bupropion. Examples include Rybelsus and Mysimba; all 5 medicines are listed on this page.

What conditions are weight loss medicines used for?

Between them, the weight loss medicines on Direct Meds are used for chronic weight management and obesity management.

Do weight loss medicines come as tablets or other forms?

Mostly as tablets, with some capsules and injection pens. The forms and strengths are listed on each product page.

How do I compare weight loss medicines?

Start with the active ingredient: there are 6 different ones in this range. Products with the same active ingredients contain the same medicine. Compare their strength, form and price per unit. Each product page's details table lists uses, how quickly it works, side effects and interactions. If you take other medicines, are pregnant or have a long-term condition, check with a doctor or pharmacist first.

Are these weight loss medicines brand-name or generic?

Mostly generic. Names such as Rybelsus and Mysimba identify the medicine: you receive a generic with the same active ingredients and strength. The generic brand and maker depend on stock.

What you will receive →

What do weight loss medicines cost in rand?

Compare each medicine, strength and pack on its product page. Prices are shown in rand, converted from US dollars, so the final rand total can change with the exchange rate. Larger packs usually cost less per unit.

Payment and prices →

Can I buy weight loss medicines over the counter in South Africa?

Yes, online. Direct Meds does not ask for a prescription to order weight loss medicines. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.

Ordering without a prescription →

How do I order weight loss medicines for delivery in South Africa?

Choose a product, strength and pack, then check out. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.

How ordering works →

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