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HIV ManagementHIV Management

Antiretroviral tablets for HIV-1 treatment fill this range, from single-ingredient options such as Tivicay and Sustiva to combination tablets such as Biktarvy, Viropil and Tenvir-em, which also covers pre-exposure prophylaxis.

Tivicay

Dolutegravir

50mg

Dolutegravir tablets for HIV-1 infection. It blocks an enzyme the virus needs to copy itself into cells.

From$8.18/ tabletView

Combivir

Lamivudine, Zidovudine

150mg + 300mg

A lamivudine and zidovudine tablet for HIV-1 infection. Both ingredients mimic natural building blocks of viral DNA, causing the chain to stop growing.

From$1.81/ tabletView

Epivir

Lamivudine

150mg

Lamivudine tablets for HIV-1 infection. They are used alongside other antiretrovirals to keep the virus under control.

From$1.51/ tabletView

Sustiva

Efavirenz

200mg · 600mg

Efavirenz tablets for HIV-1 infection. They stop the virus from replicating by blocking its reverse transcriptase enzyme.

From$5.31/ tabletView

Key points

  • Antiretroviral therapy is recommended for everyone with HIV, using single medicines or combinations to lower viral load.
  • HIV medicines are grouped into classes by the stage of the virus’s life cycle they target.
  • Combination tablets place two or three antiretroviral ingredients in a single pill, so one product can cover a full regimen.
  • This range spans prevention and treatment: most tablets treat existing HIV-1 infection, while Tenvir-em is also listed for pre-exposure prophylaxis.

Single-ingredient antiretrovirals

Tivicay contains dolutegravir, and Sustiva contains efavirenz, two antiretroviral ingredients that block different stages of HIV’s life cycle. Lamivudine is the single ingredient in Epivir, and it also appears in two of the combination tablets below.

Combination tablets

Tenofovir disoproxil and emtricitabine are paired in Tenvir-em, which is also listed for pre-exposure prophylaxis alongside HIV-1 treatment. The same two ingredients appear again in Trustiva, alongside efavirenz, and tenofovir disoproxil also appears in Viropil, alongside dolutegravir and lamivudine. Biktarvy combines bictegravir, emtricitabine and tenofovir alafenamide, a related but distinct tenofovir form, into a single combination regimen. Combivir pairs lamivudine with zidovudine.

Further reading

Which HIV medicines can I buy on Direct Meds?

Direct Meds lists 8 HIV medicines. Together they contain 8 different active ingredients, including tenofovir disoproxil, emtricitabine and lamivudine. Examples include Tenvir-em and Biktarvy; all 8 medicines are listed on this page.

What are HIV medicines used for?

Between them, the HIV medicines on Direct Meds are used for human immunodeficiency virus 1 (HIV-1) infection and pre-exposure prophylaxis.

What form do HIV medicines come in?

They come as tablets. The strengths are listed on each product page.

Which of these HIV medicines is right for me?

Start with the active ingredient: there are 8 different ones in this range. Products with the same active ingredients contain the same medicine. Compare their strength, form and price per tablet. Each product page's details table lists uses, how quickly it works, side effects and interactions. If you take other medicines, are pregnant or have a long-term condition, check with a doctor or pharmacist first.

Will I receive branded or generic HIV medicines?

Usually a generic. Names such as Biktarvy and Tivicay identify the medicine: you receive a generic with the same active ingredients and strength. Others, such as Tenvir-em and Viropil, are listed under their own names; for these you receive a branded generic or generic with the same active ingredients, depending on stock.

What you will receive →

How are HIV medicines priced?

Compare each medicine, strength and pack on its product page. Prices are shown in rand, converted from US dollars, so the final rand total can change with the exchange rate. Larger packs usually cost less per tablet.

Payment and prices →

Are HIV medicines available over the counter in South Africa?

Yes, online. Direct Meds does not ask for a prescription to order HIV medicines. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.

Ordering without a prescription →

Can I order HIV medicines online in South Africa?

Yes. Choose a product, strength and pack, then check out. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.

How ordering works →