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Overactive Bladder

Overactive bladder is a cluster of urinary symptoms that includes frequent urination, sudden strong urges to pee, waking at night to urinate, and occasional leakage.

Ditropan

Oxybutynin

2.5mg · 5mg

Oxybutynin tablets for an overactive bladder. It relaxes the bladder muscle to stop sudden urges.

From$1.59/ tabletView

Vesicare

Solifenacin

5mg · 10mg

Solifenacin tablets for overactive bladder. It calms bladder muscle spasms to reduce sudden urges.

From$2.98/ tabletView

Myrbetriq

Mirabegron

25mg · 50mg

Mirabegron tablets for overactive bladder. It relaxes the bladder muscle so it can hold more urine.

From$2.01/ tabletView

Detrol

Tolterodine

1mg · 2mg · 4mg

Tolterodine tablets for overactive bladder and urinary incontinence. It calms the bladder muscle by blocking the nerve signals that cause involuntary contractions.

From$1.98/ tabletView

Key points

  • Nocturia in overactive bladder is defined as the need to get up to pee at least two times each night, and a feeling of incomplete bladder emptying is also common.
  • The condition is common, most prevalent in people 65 and older, though it is not a normal part of aging and women may develop it around age 45.
  • It stems from detrusor muscle overactivity in the bladder wall, which can be triggered by nerve damage, infection, or hormonal changes.
  • Treatment rarely cures overactive bladder but can help; options include behavioral changes, medications, and nerve stimulation.

Medicines listed for Overactive Bladder

The four listed products are all tablets. Three contain antimuscarinic agents: Oxybutynin (Ditropan), Solifenacin (Vesicare), and Tolterodine (Detrol). The fourth, Myrbetriq, contains Mirabegron, a beta-3 adrenergic agonist. Antimuscarinics work by relaxing the detrusor muscle to reduce urgency and frequency, while Mirabegron acts on a different receptor pathway to calm bladder contractions.

Further reading