Severe Recalcitrant Nodular Acne
Severe recalcitrant nodular acne is a stubborn form of acne where deep, painful breakouts called cysts and nodules extend into the skin. Over-the-counter treatments cannot clear it.
Key points
- Nodules are large hard lumps beneath the skin surface, while cysts are the most severe type of acne spot, appearing as large pus-filled lumps resembling boils.
- Severe acne tends to produce many breakouts across the face, chest, and back, and may also appear along the jawline, neck, and sometimes the buttocks.
- Severe acne generally requires a dermatologist’s care, and isotretinoin may be discussed if initial treatments do not clear it.
Medicines listed for Severe Recalcitrant Nodular Acne
The listed products contain Isotretinoin, a retinoid that targets the causes of acne. Accutane, Accufine and Isotroin are all available as capsules, with strengths spanning 5 mg to 40 mg across the three products.


