Alfuzosin
One product sits on this shelf: Uroxatral 10 mg, an extended-release tablet of alfuzosin. The medicine eases urinary symptoms caused by Benign Prostatic Hyperplasia, an enlarged prostate.
Key points
- Alfuzosin is an alpha1 blocker: it relaxes smooth muscle in the prostate and the bladder neck, widening the passage urine travels through.
- Uroxatral is the extended-release form. The tablet releases its dose slowly across the day rather than all at once.
- Dizziness and a drop in blood pressure when standing follow from alpha1 blockade and are worth knowing before you start.
How does Alfuzosin work?
Alfuzosin blocks alpha1-adrenergic receptors in the smooth muscle of the prostate and the bladder neck. When that muscle relaxes, the urethra opens wider and urine flows with less straining. The frequent trips, weak stream and incomplete emptying that come with an enlarged prostate ease as the passage opens. The extended-release design in Uroxatral spreads the 10 mg dose over roughly 24 hours, so blood levels stay steadier than with an immediate-release tablet and the peak-related dizziness is reduced.
