Atomoxetine
Two atomoxetine products sit on this shelf: Strattera, the brand-name version from Eli Lilly, and Axepta from Torrent Pharmaceuticals. Both come as tablets in 10 mg, 18 mg, 25 mg and 40 mg strengths, listed for Attention Deficit Hyperactivity Disorder.
Key points
- Atomoxetine carries a boxed warning: in short-term trials, suicidal ideation appeared in 0.4% of children and adolescents taking it (5 of 1,357), compared with none among 851 on placebo. No suicides occurred.
- Atomoxetine is a norepinephrine reuptake inhibitor, a mechanism separate from stimulant medications. The label lists it for ADHD in children and adults, and states it is not approved for major depressive disorder. Both products are listed under ADHD & Focus.
- Drugs that reduce stomach acid, such as antacids and omeprazole, had no effect on atomoxetine absorption.
Common questions about Atomoxetine
What should I watch for when starting atomoxetine?
Patients starting atomoxetine should be monitored closely for suicidal thinking, worsening symptoms, or unusual changes in behaviour. Families and caregivers should watch for these signs and report them to the prescriber. Co-existing conditions alongside ADHD may themselves raise the risk of suicidal thoughts.
Why does atomoxetine come in four strengths?
A prescriber can match the dose to each patient’s needs across the 10 mg, 18 mg, 25 mg and 40 mg range. The label covers both children and adults with ADHD.
Further reading
What is atomoxetine used for?
Atomoxetine is used for attention deficit hyperactivity disorder in children and adults.
How does atomoxetine work?
Atomoxetine is a norepinephrine reuptake inhibitor that selectively inhibits the presynaptic norepinephrine transporter. This raises extracellular transmitter levels in the prefrontal cortex. Its mechanism is different from that of stimulant medicines.
How long does atomoxetine take to work?
Atomoxetine can take 2 to 4 weeks to start working.
What side effects can atomoxetine cause?
Common side effects include nausea, decreased appetite and drowsiness (somnolence). More serious side effects include suicidal ideation and severe liver damage (hepatotoxicity), which need immediate medical attention. Speak to your doctor or pharmacist if you are concerned.
Can atomoxetine be taken with other medicines?
Atomoxetine can interact with MAO inhibitors, fluoxetine and paroxetine. It is contraindicated with MAO inhibitor therapy. Check with your doctor or pharmacist before taking it with other medicines.
Which atomoxetine products does Direct Meds sell?
On Direct Meds, atomoxetine comes as Axepta and Strattera. Compare their forms, strengths and packs.
How much does atomoxetine cost in South Africa?
Compare the rand prices for each product, strength and pack above. Prices are converted from US dollars.
Payment and prices →Do I need a prescription for atomoxetine in South Africa?
No, not online. Direct Meds does not ask for a prescription to order atomoxetine. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Can I buy atomoxetine online in South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →