Bupropion
Two bupropion products sit on this shelf: Zyban, the 150 mg tablet for Smoking Cessation, and Mysimba, which pairs bupropion with naltrexone for Chronic Weight Management.
Key points
- Bupropion is contraindicated in anyone with a seizure disorder, and the dose is increased gradually to reduce seizure risk.
- A current or prior diagnosis of bulimia or anorexia nervosa is also a contraindication; a history counts, not only a current diagnosis.
Common questions about Bupropion
Why are there two different bupropion products here?
Zyban is bupropion alone at 150 mg, listed for smoking cessation. Mysimba adds naltrexone 8 mg to bupropion 90 mg and is listed for chronic weight management. The two products target different conditions and are not interchangeable.
Is bupropion used for depression?
Yes. Bupropion belongs to the Antidepressants class and is indicated for major depressive disorder and for preventing seasonal depressive episodes. It is sold under the brand Wellbutrin for those uses. The two products on this shelf are not listed for depression.

