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Bupropion

Two bupropion products sit on this shelf: Zyban, the 150 mg tablet for Smoking Cessation, and Mysimba, which pairs bupropion with naltrexone for Chronic Weight Management.

Zyban

Smoking Cessation

150mg

Bupropion tablets for smoking cessation. It works on the same brain chemicals that nicotine affects, easing cravings.

From$0.93/ tabletView

Mysimba

Chronic Weight Management

90mg + 8mg

Naltrexone and bupropion tablets for weight management. They work on the brain's reward system to cut food cravings.

From$2.89/ tabletView

Key points

  • Bupropion is contraindicated in anyone with a seizure disorder, and the dose is increased gradually to reduce seizure risk.
  • A current or prior diagnosis of bulimia or anorexia nervosa is also a contraindication; a history counts, not only a current diagnosis.

Common questions about Bupropion

Why are there two different bupropion products here?

Zyban is bupropion alone at 150 mg, listed for smoking cessation. Mysimba adds naltrexone 8 mg to bupropion 90 mg and is listed for chronic weight management. The two products target different conditions and are not interchangeable.

Is bupropion used for depression?

Yes. Bupropion belongs to the Antidepressants class and is indicated for major depressive disorder and for preventing seasonal depressive episodes. It is sold under the brand Wellbutrin for those uses. The two products on this shelf are not listed for depression.

Further reading

What is bupropion used for?

Bupropion alone is used for smoking cessation. When combined with naltrexone it is used for chronic weight management, and bupropion is also indicated for major depressive disorder and for preventing seasonal depressive episodes.

How does bupropion work?

Bupropion inhibits the neuronal reuptake of dopamine and norepinephrine. This stabilises synaptic arousal pathways and reduces addiction cues.

How long does bupropion take to work?

Bupropion starts to work in about 1 to 2 weeks.

What are the side effects of bupropion?

Common side effects include dry mouth, headache and nausea. Insomnia, anxiety and weight loss are also listed side effects. Seizures and suicidal ideation are serious and require immediate medical attention.

Can you drink alcohol while taking bupropion?

Alcohol can interact with bupropion. Bupropion is contraindicated during abrupt alcohol withdrawal, so ask your doctor or pharmacist before drinking alcohol.

What bupropion products are available?

On Direct Meds, bupropion comes as Zyban and Mysimba. Compare their forms, strengths and packs.

How much does bupropion cost in South Africa?

Compare the rand prices for each product, strength and pack above. Prices are converted from US dollars. Larger packs usually cost less per tablet.

Payment and prices →

Is bupropion available over the counter in South Africa?

Yes, online. Direct Meds does not ask for a prescription to order bupropion. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.

Ordering without a prescription →

Can I buy bupropion online in South Africa?

Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.

How ordering works →

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