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Ciclosporin

One ciclosporin product sits on this shelf: Ciclosporin Capsules (Neoral) in 50 mg and 100 mg. It is a calcineurin-inhibitor immunosuppressant used to prevent organ rejection and to calm severe Rheumatoid Arthritis and Psoriasis.

Medicine containing Ciclosporin

Ciclosporin Capsules

Rheumatoid Arthritis, Psoriasis

50mg · 100mg

Ciclosporin capsules for rheumatoid arthritis and psoriasis. It suppresses T-lymphocyte activity by blocking a specific cell-signalling pathway.

From$4.10/ capsuleView

Key points

  • Ciclosporin can cause nephrotoxicity and systemic hypertension at recommended doses, with risk rising with dose and duration; psoriasis patients previously treated with PUVA face an added risk of skin malignancy.
  • Regular serum creatinine monitoring is required during treatment to catch kidney changes early.
  • Ciclosporin dampens the immune system, which raises the risk of bacterial, fungal and viral infections, often involving opportunistic pathogens.

How does Ciclosporin work?

Ciclosporin (also called ciclosporin A) blocks a specific cell-signalling pathway inside T cells, the white blood cells that coordinate immune attacks. It stops these cells from releasing interleukin 2, a chemical messenger that tells other immune cells to multiply and launch an inflammatory response.

The practical effect is a quieter immune system. In transplant patients, that means the body is less likely to reject a new kidney, liver or heart. In autoimmune conditions like rheumatoid arthritis and severe psoriasis, it reduces the immune system’s attack on the body’s own tissue. This is why ciclosporin appears in Autoimmune Support alongside other immune-modulating medicines.

Further reading

FAQ

What ciclosporin products are available?

On Direct Meds, ciclosporin comes as Ciclosporin Capsules. Compare their forms, strengths and packs.

Which brands contain ciclosporin?

Ciclosporin is also sold under brand names such as Neoral. In South Africa it is also sold as Sandimmun. Names differ from country to country, so the active ingredient is the surest way to compare products.

How is ciclosporin priced?

Compare the price of each product, strength and pack above. Prices are set in US dollars and converted.

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Can I buy ciclosporin over the counter in South Africa?

Yes, online. Direct Meds does not ask for a prescription to order ciclosporin. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.

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Can I buy ciclosporin online in South Africa?

Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.

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