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Desvenlafaxine

Pristiq is the only desvenlafaxine product on this shelf, listed in 50 mg and 100 mg tablets. It is used to treat Major Depressive Disorder in adults.

Medicine containing Desvenlafaxine

Pristiq

Major Depressive Disorder

50mg · 100mg

Desvenlafaxine tablets for major depressive disorder. It raises both serotonin and norepinephrine, making it different from SSRIs that target one.

From$1.07/ tabletView

Key points

  • Desvenlafaxine is an Antidepressant in the SNRI class, the primary active metabolite of venlafaxine.
  • Combining desvenlafaxine with MAOIs, tricyclic antidepressants, triptans or St. John’s Wort can trigger serotonin syndrome, a rare but very serious condition with high mortality.
  • Abruptly stopping desvenlafaxine can cause irritability, nausea and headaches; a gradual taper is recommended.

How does Desvenlafaxine work?

Desvenlafaxine blocks the reabsorption of serotonin and norepinephrine in the brain, leaving more of both available between nerve cells. In lab studies, it is ten times more selective for serotonin than for norepinephrine, a profile similar to duloxetine. The liver breaks it down with minimal involvement of its main drug-processing enzymes, which reduces the risk of interactions with other medicines.

Further reading

FAQ

In which products can I find desvenlafaxine?

On Direct Meds, desvenlafaxine comes as Pristiq. Compare their forms, strengths and packs.

What are other names for desvenlafaxine?

In South Africa it is also sold as Exlov, Exsira and Depven. Names differ from country to country, so the active ingredient is the surest way to compare products.

How much does desvenlafaxine cost in South Africa?

Compare the price of each product, strength and pack above. Prices are set in US dollars and converted. Larger packs usually cost less per tablet.

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Is desvenlafaxine available over the counter in South Africa?

Yes, online. Direct Meds does not ask for a prescription to order desvenlafaxine. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.

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Can I buy desvenlafaxine online in South Africa?

Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.

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