Efavirenz
Two efavirenz products sit on this shelf: Sustiva, the brand-name tablet, and Trustiva, a three-drug combination. Both are listed for HIV Management and used to treat HIV-1 infection alongside other antiretrovirals.
Key points
- Efavirenz tablets must not be used as a single agent to treat HIV-1; resistant virus emerges rapidly when the drug is taken alone or added as a sole agent to a failing regimen.
- Dizziness (28%), insomnia (16%) and impaired concentration (8%) are the most common central nervous system effects, and serious psychiatric adverse experiences have been reported.
- Trustiva combines efavirenz with tenofovir disoproxil and emtricitabine in one tablet; Sustiva is efavirenz on its own.
Common questions about Efavirenz
What strengths are listed for each product?
Sustiva is listed at 200 mg and 600 mg per tablet. Trustiva is a fixed-dose combination: each tablet contains 300 mg tenofovir disoproxil, 600 mg efavirenz and 200 mg emtricitabine, so all three active ingredients are delivered in one tablet.
Can efavirenz affect how other medicines work?
Efavirenz speeds up the liver enzymes that break down many other medicines, which can lower their effectiveness. The label says efavirenz must not be taken with elbasvir and grazoprevir, and warns that other drugs broken down the same way may be affected.
Further reading
FAQ
In which products can I find efavirenz?
On Direct Meds, efavirenz comes as Sustiva and Trustiva. Compare their forms, strengths and packs.
Which brands contain efavirenz?
In South Africa it is also sold as Heftenam, Erige and Zenfar. Names differ from country to country, so the active ingredient is the surest way to compare products.
How much does efavirenz cost in South Africa?
Compare the price of each product, strength and pack above. Prices are set in US dollars and converted. Larger packs usually cost less per tablet.
Payment and prices →Can I buy efavirenz over the counter in South Africa?
Yes, online. Direct Meds does not ask for a prescription to order efavirenz. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Do you deliver efavirenz to South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →Last updated