Micardis Hct
Hypertension
40mg + 12.5mg · 80mg + 12.5mg
Telmisartan and hydrochlorothiazide tablets for high blood pressure. One part relaxes blood vessels, the other removes extra fluid.
From$1.57/ tabletView
Hydrochlorothiazide
Three hydrochlorothiazide products sit on this shelf, each pairing the thiazide diuretic at 12.5 mg with a different angiotensin II receptor blocker: Micardis HCT, Diovan HCT and Hyzaar, all tablets for hypertension.
Diovan Hct
Hypertension
80mg + 12.5mg · 160mg + 12.5mg
Valsartan and hydrochlorothiazide tablets for high blood pressure. One part relaxes vessels, the other sheds extra fluid.
From$1.63/ tabletView
Key points
- Each product pairs hydrochlorothiazide with a different angiotensin II receptor blocker: telmisartan in Micardis HCT, valsartan in Diovan HCT, and losartan in Hyzaar.
- Hydrochlorothiazide can lower blood potassium and sodium levels, and thiazides increase the urinary loss of magnesium, which may lead to low magnesium levels.
- As a sulfonamide, hydrochlorothiazide can cause an idiosyncratic reaction leading to acute angle-closure glaucoma, with sudden blurred vision or eye pain usually appearing within hours to weeks of starting treatment.
How does Hydrochlorothiazide work?
Hydrochlorothiazide is a thiazide diuretic that acts on the kidneys to reduce the amount of salt the body reabsorbs. More salt passes into the urine, and water follows it, which lowers the volume of fluid circulating through the blood vessels. Over time this reduces the pressure against vessel walls.
Lowering blood pressure in this way reduces the risk of fatal and non-fatal cardiovascular events, chiefly strokes and heart attacks. In the products listed here, hydrochlorothiazide is always paired with a second medicine that relaxes blood vessels through a different route, so the two work together to bring pressure down.
Brands and forms in this catalogue
Every product on this shelf is a tablet in the Heart & Blood Pressure category, and the hydrochlorothiazide component is fixed at 12.5 mg in all three. What changes is the partner drug and its strength: Micardis HCT pairs it with telmisartan at 40 mg or 80 mg, Diovan HCT with valsartan at 80 mg or 160 mg, and Hyzaar with losartan at 12.5 mg, 25 mg or 50 mg.
Because each combination includes a drug that acts on the renin-angiotensin system, the label carries a boxed warning: these medicines can cause injury and death to a developing fetus, and should be stopped as soon as pregnancy is detected. That warning applies to the ARB partner, not to hydrochlorothiazide on its own.