Lansoprazole
Lansoprazole, the active ingredient in Prevacid, comes in 15 mg and 30 mg tablets and is a proton pump inhibitor used to heal duodenal ulcers and relieve symptoms of gastro-oesophageal reflux disease.
Key points
- Feeling better on lansoprazole does not rule out a malignant gastric tumour; the medicine can mask symptoms and delay diagnosis.
- Lansoprazole shuts down the acid pumps in the stomach’s parietal cells, reducing both baseline and stimulated acid secretion.
- The tablets contain acid-resistant granules because lansoprazole is broken down by stomach acid, so absorption begins only after the granules leave the stomach.
How does Lansoprazole work?
Lansoprazole belongs to a class called proton pump inhibitors (PPIs). It concentrates inside the stomach’s acid-producing cells and switches off the pumps at the final step of acid formation, reducing secretion whether the stomach is at rest or stimulated by food. The effect is reversible: once the drug clears, the pumps resume normal output.
Lansoprazole does not block histamine or nerve-signal pathways the way older acid-reducing medicines do. It acts at a single point in the acid-production chain. You will find it listed under Digestive Health.
