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Losartan

Two losartan products sit on this Heart & Blood Pressure shelf: Cozaar, the brand-name tablet for Hypertension in 25 mg, 50 mg and 100 mg strengths, and Hyzaar, which pairs losartan with hydrochlorothiazide.

Cozaar

Hypertension, Diabetic Nephropathy

25mg · 50mg · 100mg

Losartan tablets for high blood pressure and diabetic kidney disease. It blocks angiotensin II receptors, relaxing artery walls and reducing salt retention.

From$0.73/ tabletView

Hyzaar

Hypertension, Stroke Prevention

12.5mg + 12.5mg · 25mg + 12.5mg · 50mg + 12.5mg

Losartan and hydrochlorothiazide tablets for high blood pressure and stroke prevention. Losartan blocks a constricting hormone, the diuretic removes extra fluid.

From$0.51/ tabletView

Key points

  • Losartan carries a boxed warning for fetal toxicity; medicines acting on the renin-angiotensin system can cause injury and death to a developing fetus.
  • In type 2 diabetes with kidney disease, losartan slows the damage, and the blood-pressure reduction lowers the risk of Stroke Prevention and heart attack.
  • Anyone with a past episode of angioedema (swelling of the face, lips, throat or tongue) should be closely monitored while taking losartan.

Common questions about Losartan

What does Hyzaar add that Cozaar does not?

Hyzaar pairs losartan with hydrochlorothiazide, a second blood-pressure medicine, in one tablet. Cozaar contains losartan alone. The combination matters because many people need more than one medicine to reach their blood pressure goal, and taking both in a single tablet simplifies the routine.

Why does Cozaar come in three strengths?

Cozaar is listed at 25 mg, 50 mg and 100 mg. The three strengths cover a range of doses for different responses. Many people need more than one medicine to reach their blood pressure goal, so Hyzaar pairs losartan and hydrochlorothiazide in three fixed combinations.

Further reading