Mebeverine
Mebeverine (sold as Colospa) relaxes the smooth muscle in your gut to ease the cramping and spasms that come with Irritable Bowel Syndrome. Colospa is the only product listed, in 135 mg and 200 mg capsules.
Medicine containing Mebeverine
Key points
- Acts directly on gut muscle without slowing normal digestion, targeting Gastrointestinal Spasm rather than the whole bowel.
- Rare but serious allergic reactions including throat swelling and difficulty breathing have been reported.
- The 200 mg capsule is not recommended under 18, as safety data for younger patients is limited.
How does mebeverine work?
The exact way mebeverine calms gut muscle is not fully understood, but it appears to work through several routes at once: it reduces the flow of ions through muscle cell channels, blocks the reabsorption of noradrenaline, and has a mild local anaesthetic effect on the muscle itself. What sets it apart from older antispasmodics is that it acts locally on the bowel wall without producing the dry mouth, blurred vision or urinary retention that anticholinergic medicines cause. The 200 mg modified release capsule is absorbed quickly and releases the medicine over several hours. Colospa is listed under Digestive Health.
Further reading
FAQ
What mebeverine products are available?
On Direct Meds, mebeverine comes as Colospa. Compare their forms, strengths and packs.
Which brands contain mebeverine?
In South Africa it is also sold as Bevispas, Mebestend and Colofac. Names differ from country to country, so the active ingredient is the surest way to compare products.
How is mebeverine priced?
Compare the price of each product, strength and pack above. Prices are set in US dollars and converted.
Payment and prices →Can I buy mebeverine over the counter in South Africa?
Yes, online. Direct Meds does not ask for a prescription to order mebeverine. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Can I buy mebeverine online in South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →Last updated