Methylprednisolone
Methylprednisolone, sold as Medrol, is a corticosteroid tablet listed in four strengths from 4 mg to 32 mg, used for Inflammatory Conditions and Allergic States.
Key points
- Becoming seriously ill or undergoing surgery while on methylprednisolone may require a temporary increase in dose rather than a decrease; tell any treating clinician you take it.
- For less severe conditions, the label notes that alternate-day therapy may be possible.
How does Methylprednisolone work?
Methylprednisolone (Medrol) mimics cortisol, the hormone your adrenal glands produce naturally. It reduces the release of chemicals that cause swelling, redness and itching, and it dampens the immune signals that drive allergic reactions. The molecule enters cells and shifts which genes are read, turning down the inflammatory cascade at its source.
Further reading
What is methylprednisolone used for?
Methylprednisolone is used for inflammatory conditions and allergic states. It is also used for endocrine disorders.
How long does methylprednisolone take to work?
Methylprednisolone starts to work in 1 to 2 hours. Its effect lasts for 18 to 36 hours.
What are the side effects of methylprednisolone?
Common side effects include increased appetite, indigestion and insomnia. Moderate side effects can include elevated glucose, weight gain and fluid retention. Serious side effects include adrenal suppression and osteonecrosis, which require immediate medical attention, so speak to a doctor or pharmacist.
Can methylprednisolone be taken with other medicines?
Methylprednisolone may interact with insulin, ketoconazole and NSAIDs. If you take any of these, speak to a doctor or pharmacist.
Who should not take methylprednisolone?
Methylprednisolone should not be used by anyone with a systemic fungal infection, and it should not be used during live vaccine administration.
In which products can I find methylprednisolone?
On Direct Meds, methylprednisolone comes as Medrol. Compare their forms, strengths and packs.
How is methylprednisolone priced?
Compare the rand prices for each product, strength and pack above. Prices are converted from US dollars. Larger packs usually cost less per tablet.
Payment and prices →Do I need a prescription for methylprednisolone in South Africa?
No, not online. Direct Meds does not ask for a prescription to order methylprednisolone. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Can I buy methylprednisolone online in South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →