Modafinil
Modalert is the only modafinil product on this shelf, available in 100 mg and 200 mg tablets. It is used to improve wakefulness in adults with narcolepsy, obstructive sleep apnoea or shift work disorder.
Key points
- In obstructive sleep apnoea, modafinil treats the excessive sleepiness and is not a treatment for the underlying obstruction.
- Stop modafinil at the first sign of rash, unless the rash is clearly not drug-related, as serious rash requiring hospitalisation has been reported.
- Modafinil may reduce blood concentrations of ciclosporin.
What modafinil is used for
Modafinil is a wakefulness-promoting agent licensed for three sleep-disorder indications: narcolepsy, obstructive sleep apnoea and shift work disorder. Modalert sits in the ADHD & Focus category on this site, where readers researching attention-related options may encounter it.
Further reading
What is modafinil used for?
Modafinil is used to improve wakefulness in adults with narcolepsy, obstructive sleep apnoea or shift work disorder. In obstructive sleep apnoea, it treats the excessive sleepiness and not the underlying obstruction.
How does modafinil work?
Modafinil selectively blocks dopamine transporter proteins, which increases how long dopamine remains active in the central wakefulness centres.
How long does modafinil take to work?
Modafinil starts working in about 1 to 2 hours. Its effects last for 10 to 12 hours.
What are the side effects of modafinil?
Common side effects include headache, nausea and dry mouth. Insomnia, anxiety and dizziness can also occur. Serious reactions such as Stevens-Johnson syndrome and severe psychiatric mania need immediate medical attention, so speak to your doctor or pharmacist if you are concerned.
Who should not take modafinil?
Modafinil should not be taken by people with severe cardiovascular disease or hypersensitivity to modafinil.
In which products can I find modafinil?
On Direct Meds, modafinil comes as Modalert. Compare their forms, strengths and packs.
How much does modafinil cost in South Africa?
Compare the rand prices for each product, strength and pack above. Prices are converted from US dollars. Larger packs usually cost less per tablet.
Payment and prices →Can I buy modafinil over the counter in South Africa?
Yes, online. Direct Meds does not ask for a prescription to order modafinil. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Can I buy modafinil online in South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →Related articles
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