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Nitrofurantoin

Nitrofurantoin, an Antibiotics medicine sold as Macrodantin and as generic tablets, treats uncomplicated Acute Cystitis and other lower urinary tract infections. One product sits on this shelf: Nitrofurantoin Tablets in 50 mg and 100 mg.

Nitrofurantoin Tablets

Acute Cystitis, Urinary Tract Infections

50mg · 100mg

Nitrofurantoin tablets for bladder infections and other UTIs. It concentrates in the urine to act directly on the bacteria.

From$0.87/ tabletView

Key points

  • Several major guidelines recommend nitrofurantoin as the first treatment for uncomplicated lower Urinary Tract Infections.
  • Nitrofurantoin is not suitable if you have significant kidney problems (creatinine clearance below 60 mL/min), are in the last month of pregnancy, or are treating a baby under one month old.
  • Macrodantin is the brand-name version; the generic tablets contain the same active ingredient.

How does nitrofurantoin work?

Inside bacteria, nitrofurantoin is converted into reactive compounds that block the cell’s ability to copy DNA, build RNA, and assemble its outer wall. This broad attack may explain why resistance to nitrofurantoin remains rare.

Further reading