Skip to content

Prednisolone

Prednisolone (sold as Panafcortelone) is a corticosteroid used for Inflammatory Conditions and Allergic States. One tablet product comes in four strengths, from 5 mg to 40 mg.

Prednisolone Tablets

Inflammatory Conditions, Allergic States

5mg · 10mg · 20mg · 40mg

Prednisolone tablets for inflammatory conditions and allergies. It dampens the immune response, so it should be tapered off rather than stopped abruptly.

From$0.50/ tabletView

Key points

  • Stopping prednisolone after more than three weeks at 5 mg or equivalent should not be abrupt; a taper is needed.
  • Illness or unusual stress while on corticosteroid therapy may require a higher dose rather than a lower one.
  • Prednisolone also treats adrenal insufficiency and congenital adrenal hyperplasia as an endocrine replacement.

Stopping and stress dosing

Prednisolone is a corticosteroid in the Pain & Anti-inflammatories category that calms the immune system and reduces inflammation. It also suppresses the adrenal glands’ own steroid production, so after three weeks or more of daily use the dose needs to be tapered rather than stopped. A fever, infection or surgery can leave the body unable to mount its usual stress response, meaning the dose may need to be increased for a short period rather than reduced. For less severe conditions, an alternate-day schedule may be possible to limit this suppression.

Further reading

What is prednisolone used for?

Prednisolone is used for inflammatory conditions and allergic states. It is also used for autoimmune disorders, adrenal insufficiency and congenital adrenal hyperplasia.

How long does prednisolone take to work?

Prednisolone may start to work within 1 to 2 hours. Its effects may last for 18 to 36 hours.

What are the side effects of prednisolone?

Common side effects include increased appetite, insomnia and indigestion. Moderate side effects can include weight gain, elevated glucose and fluid retention. Serious side effects include adrenal suppression and severe bone mineral density loss, which need immediate medical attention. Speak to your doctor or pharmacist if you notice any of these.

Can prednisolone be taken with other medicines?

Prednisolone may interact with insulin, warfarin and aspirin. Check with your doctor or pharmacist before taking other medicines.

Who should not take prednisolone?

Prednisolone should not be taken by people with systemic fungal infections or those receiving live vaccines at the same time.

In which products can I find prednisolone?

On Direct Meds, prednisolone comes as Prednisolone Tablets. Compare their forms, strengths and packs.

Which brands contain prednisolone?

Prednisolone is also sold under brand names such as Panafcortelone. Names differ from country to country, so the active ingredient is the surest way to compare products.

How much does prednisolone cost in South Africa?

Compare the rand prices for each product, strength and pack above. Prices are converted from US dollars. Larger packs usually cost less per tablet.

Payment and prices →

Can I buy prednisolone over the counter in South Africa?

Yes, online. Direct Meds does not ask for a prescription to order prednisolone. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.

Ordering without a prescription →

Can I buy prednisolone online in South Africa?

Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.

How ordering works →