Sertraline
Sertraline, sold as Zoloft, is an SSRI antidepressant that comes in 25 mg, 50 mg and 100 mg tablets for major depressive disorder and panic disorder.
Medicine containing Sertraline
Key points
- Beyond depression and panic, sertraline is also used for obsessive-compulsive disorder, post-traumatic stress disorder, social anxiety disorder and premenstrual dysphoric disorder.
- It carries a boxed warning that it may increase the risk of suicidal thoughts in people under 24, especially during the first few months of treatment or when the dose changes.
- Do not take sertraline with monoamine oxidase inhibitors such as phenelzine or selegiline, or within two weeks of stopping them.
How does Sertraline work?
Sertraline belongs to the antidepressants class known as selective serotonin reuptake inhibitors. It increases the amount of serotonin in the brain, a natural chemical linked to mood. When serotonin levels are more balanced, stress and negative thought patterns may ease over time.
Sertraline does not stimulate the body to produce more serotonin. It slows the reabsorption of serotonin already present, so more stays active between nerve cells. This is textbook SSRI pharmacology and applies to every sertraline product on the shelf, including Zoloft.
Further reading
FAQ
What sertraline products are available?
On Direct Meds, sertraline comes as Zoloft. Compare their forms, strengths and packs.
Which brands contain sertraline?
In South Africa it is also sold as Serdep and Serlife. Names differ from country to country, so the active ingredient is the surest way to compare products.
How much does sertraline cost in South Africa?
Compare the price of each product, strength and pack above. Prices are set in US dollars and converted. Larger packs usually cost less per tablet.
Payment and prices →Is sertraline available over the counter in South Africa?
Yes, online. Direct Meds does not ask for a prescription to order sertraline. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Can I buy sertraline online in South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →Last updated