Udenafil
Udenafil is a PDE5 inhibitor for erectile dysfunction, listed here as Zudena in a single 100 mg tablet. It relaxes blood vessels to increase blood flow during sexual stimulation.
Key points
- Udenafil belongs to the PDE5 inhibitor class, the same group as sildenafil, tadalafil and vardenafil.
- Do not take udenafil with nitrates or nitroglycerin in any form; the combination can cause a dangerous drop in blood pressure.
- Use udenafil with caution if you have had a heart attack, stroke or life-threatening arrhythmia in the past six months, or if you take alpha-blockers.
How does Udenafil work?
Udenafil blocks the enzyme phosphodiesterase-5 (PDE5) in the smooth muscle cells of blood vessels. By preventing PDE5 from breaking down cGMP, the drug allows those muscles to relax and widen, increasing blood flow where it is needed.
The liver breaks down udenafil through the CYP3A pathway, and the body excretes it as metabolites in the stool. PDE5 inhibitors do not target only one receptor, so side effects tend to be dose-dependent.
Further reading
What is udenafil used for?
Udenafil is used to treat erectile dysfunction. It is a PDE5 inhibitor, the same class of medicine as sildenafil, tadalafil and vardenafil.
How long does udenafil take to work?
Udenafil starts to work within 30 to 60 minutes. Its effects can last for 12 to 24 hours.
What are the side effects of udenafil?
Common side effects include headache, flushing and indigestion (dyspepsia), and some people may get nasal congestion, dizziness or minor blurred vision. A serious side effect is priapism, which needs immediate medical attention, so speak to your doctor or pharmacist if you are concerned.
Can udenafil be taken with other medicines?
Udenafil interacts with nitrates, alpha blockers and ketoconazole. Do not take it with nitrates as this can cause a dangerous drop in blood pressure. Check with your doctor or pharmacist before taking it with other medicines.
Who should not take udenafil?
Do not take udenafil if you use organic nitrates, have severe cardiac failure or unstable blood pressure. Use it with caution if you have had a heart attack, stroke or life-threatening arrhythmia in the past six months, or if you take alpha-blockers. Speak to your doctor or pharmacist if you are unsure.
What udenafil products are available?
On Direct Meds, udenafil comes as Zudena. Compare their forms, strengths and packs.
How much does udenafil cost in South Africa?
Compare the rand prices for each product, strength and pack above. Prices are converted from US dollars. Larger packs usually cost less per tablet.
Payment and prices →Can I buy udenafil over the counter in South Africa?
Yes, online. Direct Meds does not ask for a prescription to order udenafil. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Do you deliver udenafil to South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →