Velpatasvir
Velpatasvir (Epclusa) is an antiviral that stops hepatitis C from multiplying. Velpanat is the one product here, a 400 mg + 100 mg tablet pairing velpatasvir with sofosbuvir.
Medicine containing Velpatasvir
Key points
- Hepatitis B reactivation is a serious risk: if you have ever had hepatitis B, this combination may worsen it to a life-threatening level.
- Velpatasvir is an NS5A replication complex inhibitor, blocking a protein the virus needs to assemble its genetic material.
- Velpanat, made by Natco Pharma, is the generic version of Epclusa, the brand-name product for this combination.
How does velpatasvir work?
Velpatasvir and sofosbuvir attack the hepatitis C virus at two different points. Sofosbuvir is an NS5B polymerase inhibitor that stops the virus from copying its RNA, while velpatasvir is an NS5A inhibitor that blocks a protein needed to assemble new viral particles. The two drugs prevent the virus from building complete copies of itself, which is why the combination is used to treat chronic hepatitis C. This dual mechanism sits within the broader antivirals category of medicines that target specific steps in a virus’s life cycle.
Further reading
FAQ
In which products can I find velpatasvir?
On Direct Meds, velpatasvir comes as Velpanat. Compare their forms, strengths and packs.
What are other names for velpatasvir?
Velpatasvir is also sold under brand names such as Epclusa. Names differ from country to country, so the active ingredient is the surest way to compare products.
How is velpatasvir priced?
Compare the price of each product, strength and pack above. Prices are set in US dollars and converted.
Payment and prices →Do I need a prescription for velpatasvir in South Africa?
No, not online. Direct Meds does not ask for a prescription to order velpatasvir. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Where can I buy velpatasvir in South Africa?
On Direct Meds: choose the product, strength and pack, then check out. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →Last updated