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Vortioxetine

Trintellix is the only vortioxetine product on this shelf, a 10 mg tablet used to treat Major Depressive Disorder in adults. It sits in a class of Antidepressants called serotonin modulators, which work on serotonin in a different way from SSRIs.

Trintellix

Major Depressive Disorder

10mg

Vortioxetine tablets for major depressive disorder. It targets serotonin reuptake and receptors to help balance mood.

From$1.79/ tabletView

Key points

  • Vortioxetine raises serotonin levels in the brain, a natural substance that maintains mental balance.
  • It may increase the risk of suicidal thoughts in people under 24, particularly in the first few months of treatment or when the dose changes.
  • Do not take vortioxetine with MAO inhibitors; at least 14 days must pass after stopping an MAOI before starting it.

How does Vortioxetine work?

Vortioxetine works on serotonin in two ways at once. It blocks the serotonin transporter, keeping more serotonin available in the brain, and it also acts directly on several serotonin receptor types. This combined action sets serotonin modulators apart from SSRIs, which only block the transporter. The result is a broader effect on the brain circuits involved in mood.

Further reading