
Trintellix
Major Depressive Disorder
10mg
Vortioxetine tablets for major depressive disorder. It targets serotonin reuptake and receptors to help balance mood.
Trintellix is the only vortioxetine product on this shelf, a 10 mg tablet used to treat Major Depressive Disorder in adults. It sits in a class of Antidepressants called serotonin modulators, which work on serotonin in a different way from SSRIs.

Major Depressive Disorder
10mg
Vortioxetine tablets for major depressive disorder. It targets serotonin reuptake and receptors to help balance mood.
Vortioxetine works on serotonin in two ways at once. It blocks the serotonin transporter, keeping more serotonin available in the brain, and it also acts directly on several serotonin receptor types. This combined action sets serotonin modulators apart from SSRIs, which only block the transporter. The result is a broader effect on the brain circuits involved in mood.
On Direct Meds, vortioxetine comes as Trintellix. Compare their forms, strengths and packs.
In South Africa it is also sold as Vorellix, Brintellix and Brivor. Names differ from country to country, so the active ingredient is the surest way to compare products.
Compare the price of each product, strength and pack above. Prices are set in US dollars and converted. Larger packs usually cost less per tablet.
Payment and prices →No, not online. Direct Meds does not ask for a prescription to order vortioxetine. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →On Direct Meds: choose the product, strength and pack, then check out. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →Last updated

22 Sept 2026 ⋅ 4 min read
What vortioxetine studies show about depression, cognitive symptoms and sexual side effects, with South African Brintellix information and practical trade-offs.
Read guide