Lioresal
Baclofen tablets for spasticity and muscle spasms. It calms the overactive reflexes that keep muscles tight.
- Category
- Pain & Anti-inflammatories
- Active ingredient
- Baclofen
- Route
- Oral use
- Form
- Tablet
- Strengths
- 10mg · 25mg
Lioresal is the reference name. You receive a generic with the same active ingredient and strength.
No prescription needed: we place your order for Lioresal on your behalf.
- Conditions
- Spasticity · Muscle Spasms
- Alternative names
- baclofen
- Therapeutic class
- Skeletal Muscle Relaxant
- Pharmacological class
- GABA-B Receptor Agonist
- Known off-label uses
- hiccups
- Contraindications
- hypersensitivity to baclofen
- Minor side effects
- somnolence; dizziness; nausea
- Moderate side effects
- muscle weakness; fatigue; confusion
- Dosage forms
- Tablet
- Administration route
- Oral use
- Originator
- Novartis
- Onset Time
- 1–2 hours
- Duration
- 4–8 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Alcohol; Antihistamines; CNS Depressants
- Age restrictions
- Approved for children over two years and adults.
Serious side effects
seizure, requires immediate medical attention; severe respiratory depression, requires immediate medical attention
Patient summary
Baclofen tablets for spasticity and muscle spasms. It calms the overactive reflexes that keep muscles tight.
Mechanism of action
Acts at spinal cord level by binding to GABA-B receptors, reducing excitatory spinal reflexes to relax skeletal muscles.
Pregnancy and breastfeeding
Pregnancy: Use with caution. Breastfeeding: Confirm breastfeeding suitability with a qualified clinician or pharmacist before use.
Is the Lioresal on Direct Meds a generic?
Yes, you receive a generic. Lioresal is the original brand, made by Novartis, and Direct Meds uses the name to identify the medicine; the generic has the same active ingredient (baclofen) at the strength you choose. The generic brand and manufacturer depend on available stock.
How much does Lioresal cost in South Africa?
The price varies with strength and pack size. Lioresal comes in 10mg and 25mg strengths, in packs of 30 to 360 tablets, and the price of every option is shown above in rand, converted from US dollars. Larger packs cost less per tablet.
Payment and prices →What is Lioresal used for?
Lioresal contains baclofen, used for spasticity and muscle spasms.
How quickly does Lioresal work?
Baclofen usually starts to work within 1 to 2 hours, and its effect lasts about 4 to 8 hours. This varies from person to person.
What are the side effects of Lioresal?
The common side effects of baclofen are drowsiness (somnolence), dizziness and nausea. Less common ones include muscle weakness, fatigue and confusion. Serious but less common side effects include seizure and severe respiratory depression, which need urgent medical attention.
Is it OK to drink alcohol while taking Lioresal?
Alcohol can interact with baclofen, so check with a doctor or pharmacist before you drink while taking Lioresal.
Which medicines interact with Lioresal?
Baclofen can interact with antihistamines and CNS depressants. Tell your doctor or pharmacist about every medicine you take before you start taking Lioresal.
Is Lioresal available over the counter in South Africa?
Online, yes: Direct Meds does not ask for a prescription to order Lioresal. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Can I buy Lioresal online in South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →What you will receive
Lioresal names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Baclofen at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.