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Nexium

Nexium

Esomeprazole

Esomeprazole capsules for acid reflux and peptic ulcers. They reduce stomach acid by switching off the acid pumps.

Active ingredient
Esomeprazole
Route
Oral use
Form
Capsule
Strengths
20mg · 40mg

Nexium is the reference name. You receive a generic with the same active ingredient and strength.

No prescription needed: we place your order for Nexium on your behalf.

Alternative names
esomeprazole
Therapeutic class
Proton Pump Inhibitor (PPI)
Pharmacological class
Gastric Acid Inhibitor
Contraindications
concurrent use of rilpivirine; hypersensitivity to proton pump inhibitors
Minor side effects
headache; diarrhoea; nausea
Moderate side effects
flatulence; abdominal pain; dry mouth
Dosage forms
Capsule
Administration route
Oral use
Originator
AstraZeneca
Onset Time
1–2 hours
Duration
24 hours
Storage instructions
Store below 25°C. Keep bottle dry.
Drug interactions
Rilpivirine; Ketoconazole; Clopidogrel
Age restrictions
Approved for paediatric and adult populations.
Serious side effects

acute interstitial nephritis, requires immediate medical attention; clostridioides difficile-associated diarrhoea, requires immediate medical attention; severe hypomagnesaemia, requires immediate medical attention

Patient summary

Esomeprazole capsules for acid reflux and peptic ulcers. They reduce stomach acid by switching off the acid pumps.

Mechanism of action

Inhibits gastric H+/K+-ATPase proton pumps, raising the pH of the gastric lumen to protect structural linings.

Pregnancy and breastfeeding

Pregnancy: Suitability during pregnancy depends on the specific medicine and individual circumstances. Confirm with a qualified clinician or pharmacist before use. Breastfeeding: Consult a doctor.

Is the Nexium on Direct Meds a generic?

Yes, you receive a generic. Nexium is the original brand, made by AstraZeneca, and Direct Meds uses the name to identify the medicine; the generic has the same active ingredient (esomeprazole) at the strength you choose. The generic brand and manufacturer depend on available stock.

What is another name for esomeprazole?

In South Africa, esomeprazole is also sold under brand names such as Nexipraz.

How much does Nexium cost in South Africa?

Nexium comes in 20mg and 40mg strengths, in packs of 30 to 360 capsules, and the price of every option is shown above in rand, converted from US dollars. Larger packs cost less per capsule.

Payment and prices →

What is Nexium used for?

Nexium contains esomeprazole, used for gastro-oesophageal reflux disease, peptic ulcer disease and erosive oesophagitis.

How long does Nexium take to work?

Esomeprazole usually starts to work within 1 to 2 hours, and its effect lasts about 24 hours. The exact timing differs between people.

What are the side effects of Nexium?

The common side effects of esomeprazole are headache, diarrhoea and nausea. Less common ones include flatulence, abdominal pain and dry mouth. Serious but less common side effects include acute interstitial nephritis, Clostridioides difficile-associated diarrhoea and severe hypomagnesaemia, which need urgent medical attention.

Which medicines interact with Nexium?

Esomeprazole can interact with rilpivirine, ketoconazole and clopidogrel. Tell your doctor or pharmacist about every medicine you take before you start taking Nexium.

Do I need a prescription to buy Nexium in South Africa?

No, not online: Direct Meds does not ask for a prescription to order Nexium. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.

Ordering without a prescription →

Where can I buy Nexium in South Africa?

On Direct Meds: choose the strength and pack, then check out. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.

How ordering works →

What you will receive

Nexium names the medicine you are looking for. What ships is a generic version of it.

  • A generic containing Esomeprazole at the strength you pick.
  • Which generic brand and maker ships depends on stock and destination.
  • Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.

How we compare medicine brands and generics