Skip to content
Nolvadex

Nolvadex

Tamoxifen

Tamoxifen tablets for breast cancer. It blocks oestrogen from attaching to hormone-sensitive breast cancer cells.

Active ingredient
Tamoxifen
Route
Oral use
Form
Tablet
Strengths
10mg · 20mg

Nolvadex is the reference name. You receive a generic with the same active ingredient and strength.

No prescription needed: we place your order for Nolvadex on your behalf.

Condition
Breast Cancer
Alternative names
tamoxifen
Therapeutic class
Selective Oestrogen Receptor Modulator (SERM)
Pharmacological class
Antineoplastic
Known off-label uses
ovulation induction
Minor side effects
hot flushes; nausea; fatigue
Moderate side effects
vaginal discharge; fluid retention; menstrual irregularities
Dosage forms
Tablet
Administration route
Oral use
Originator
AstraZeneca
Onset Time
4–8 weeks
Duration
24 hours
Storage instructions
Store below 25°C.
Drug interactions
Warfarin; Rifampin; Paroxetine
Age restrictions
Approved for adults.
Contraindications

pregnancy; history of deep vein thrombosis; concurrent coumarin-type anticoagulants

Serious side effects

thromboembolism, requires immediate medical attention; endometrial carcinoma, requires immediate medical attention; severe retinopathy, requires immediate medical attention

Patient summary

Tamoxifen tablets for breast cancer. It blocks oestrogen from attaching to hormone-sensitive breast cancer cells.

Mechanism of action

Competitively binds to oestrogen receptors in target tissues, blocking gene transcription in hormone-sensitive cells.

Pregnancy and breastfeeding

Pregnancy: High risk of fetal toxicity. Do not use during pregnancy. Breastfeeding: Contraindicated.

Is the Nolvadex on Direct Meds a generic?

Yes, you receive a generic. Nolvadex is the original brand, made by AstraZeneca, and Direct Meds uses the name to identify the medicine; the generic has the same active ingredient (tamoxifen) at the strength you choose. The generic brand and manufacturer depend on available stock.

How is Nolvadex priced?

The price varies with strength and pack size. Nolvadex comes in 10mg and 20mg strengths, in packs of 60 to 360 tablets, and the price of every option is shown above in rand, converted from US dollars. Larger packs cost less per tablet.

Payment and prices →

What other names is Nolvadex sold under?

On Direct Meds the same ingredient is also sold as Tamoxifen Tablets.

What is Nolvadex used for?

Nolvadex contains tamoxifen, used for breast cancer.

How long does Nolvadex take to work?

Tamoxifen usually starts to work within 4 to 8 weeks. This varies from person to person.

Does Nolvadex have side effects?

Yes. The common side effects of tamoxifen are hot flushes, nausea and fatigue. Less common ones include vaginal discharge, fluid retention and menstrual irregularities. Serious but less common side effects include thromboembolism, endometrial carcinoma and severe retinopathy, which need urgent medical attention.

What does Nolvadex interact with?

Tamoxifen can interact with warfarin, rifampicin and paroxetine. Tell your doctor or pharmacist about every medicine you take before you start taking Nolvadex.

Is Nolvadex available over the counter in South Africa?

Online, yes: Direct Meds does not ask for a prescription to order Nolvadex. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.

Ordering without a prescription →

Can I buy Nolvadex online in South Africa?

Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.

How ordering works →

What you will receive

Nolvadex names the medicine you are looking for. What ships is a generic version of it.

  • A generic containing Tamoxifen at the strength you pick.
  • Which generic brand and maker ships depends on stock and destination.
  • Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.

How we compare medicine brands and generics