Phenergan
Promethazine tablets for allergies and motion sickness. It blocks histamine and dampens the brain's nausea signal.
- Category
- Sleep Management
- Active ingredient
- Promethazine
- Route
- Oral use
- Form
- Tablet
- Strengths
- 25mg
Phenergan is the reference name. You receive a generic with the same active ingredient and strength.
No prescription needed: we place your order for Phenergan on your behalf.
- Conditions
- Allergic States · Motion Sickness · Nausea and Vomiting
- Alternative names
- promethazine
- Therapeutic class
- Phenothiazine Antihistamine; Antiemetic
- Pharmacological class
- First-Generation Antihistamine
- Known off-label uses
- preoperative sedation
- Contraindications
- children under two years; comatose states; severe respiratory depression
- Minor side effects
- somnolence; dry mouth; dizziness
- Moderate side effects
- constipation; blurred vision; tachycardia
- Dosage forms
- Tablet
- Administration route
- Oral use
- Originator
- Wyeth
- Onset Time
- 20–30 minutes
- Duration
- 4–12 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Alcohol; CNS Depressants; Anticholinergics
- Age restrictions
- Contraindicated in children under two years due to fatal respiratory risk.
Serious side effects
severe respiratory depression, requires immediate medical attention; neuroleptic malignant syndrome, requires immediate medical attention
Patient summary
Promethazine tablets for allergies and motion sickness. It blocks histamine and dampens the brain's nausea signal.
Mechanism of action
Blocks central H1 histamine receptors and dopamine receptors in the CTZ, reducing motion sickness and allergic flares.
Pregnancy and breastfeeding
Pregnancy: Use if potential benefits exceed risks. Breastfeeding: Not recommended.
Is the Phenergan on Direct Meds a generic?
Yes, you receive a generic. Phenergan is the original brand, made by Wyeth, and Direct Meds uses the name to identify the medicine; the generic has the same active ingredient (promethazine) at the same strength. The generic brand and manufacturer depend on available stock.
How much does Phenergan cost in South Africa?
The price varies with pack size. Phenergan comes in a 25mg strength, in packs of 90 to 360 tablets, and the price of every option is shown above in rand, converted from US dollars. Larger packs cost less per tablet.
Payment and prices →What is Phenergan used for?
Phenergan contains promethazine, used for allergic states, motion sickness and nausea and vomiting.
How long does Phenergan take to work?
Promethazine usually starts to work within 20 to 30 minutes, and its effect lasts about 4 to 12 hours. The exact timing differs between people.
Does Phenergan have side effects?
Yes. The common side effects of promethazine are drowsiness (somnolence), dry mouth and dizziness. Less common ones include constipation, blurred vision and tachycardia. Serious but less common side effects include severe respiratory depression and neuroleptic malignant syndrome, which need urgent medical attention.
Is it OK to drink alcohol while taking Phenergan?
Alcohol can interact with promethazine, so check with a doctor or pharmacist before you drink while taking Phenergan.
What does Phenergan interact with?
Promethazine can interact with CNS depressants and anticholinergics. Tell your doctor or pharmacist about every medicine you take before you start taking Phenergan.
Is Phenergan available over the counter in South Africa?
Online, yes: Direct Meds does not ask for a prescription to order Phenergan. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Can I buy Phenergan online in South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →What you will receive
Phenergan names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Promethazine at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.