VFEND
Voriconazole tablets for invasive aspergillosis and systemic candidiasis. It disrupts fungal cell membranes to stop the infection.
All strengths and pack prices
| Strength | Pack | Price | Per unit |
|---|---|---|---|
| 200mg | 4 tablets | $253.00 | $63.25 |
| 200mg | 8 tablets | $430.00 | $53.75 |
| 200mg | 12 tablets | $608.00 | $50.67 |
- Category
- Antifungals
- Active ingredient
- Voriconazole
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 200mg
VFEND is the reference name. You receive a generic with the same active ingredient and strength.
No prescription needed: we place your order for VFEND on your behalf.
- Therapeutic class
- Triazole Antifungal
- Pharmacological class
- Antifungal
- Precautions and warnings
- avoid prolonged sun exposure; monitor liver function; monitor visual function
- Minor side effects
- visual disturbances; nausea; vomiting; rash
- Moderate side effects
- elevated liver enzymes; peripheral oedema; headache
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Originator
- Pfizer
- Onset time
- 1–2 hours
- Duration
- 12 hours
- Storage instructions
- Store at room temperature.
- Drug interactions
- rifampicin; carbamazepine; pimozide; quinidine
- Age restrictions
- Use with caution in paediatric patients.
Contraindications
hypersensitivity to voriconazole; concurrent use of rifampicin; concurrent use of carbamazepine
Serious side effects
hepatotoxicity, requires immediate medical attention; photosensitivity, requires immediate medical attention; qt prolongation, requires immediate medical attention
Patient summary
Voriconazole tablets for invasive aspergillosis and systemic candidiasis. It disrupts fungal cell membranes to stop the infection.
Mechanism of action
Voriconazole inhibits fungal cytochrome P450-dependent 14-alpha-sterol demethylase, which is vital for fungal ergosterol biosynthesis, effectively disrupting fungal cell membrane formation.
Pregnancy and breastfeeding
Pregnancy: Use is not recommended unless clearly necessary. Breastfeeding: Discontinue breastfeeding during treatment.
FAQ
Will I receive the original VFEND?
No. VFEND is the original brand, made by Pfizer, and Direct Meds uses the name to identify the medicine: you receive a generic with the same active ingredient (voriconazole) at the same strength. The generic brand and manufacturer depend on available stock.
How is VFEND priced?
It depends on the pack size. VFEND comes in a 200mg strength, in packs of 4 to 12 tablets, and the price of every option is shown above. Prices are set in US dollars and converted. Larger packs cost less per tablet.
Payment and prices →What is VFEND used for?
VFEND contains voriconazole, used for invasive aspergillosis, systemic candidiasis and oesophageal candidiasis.
How long does VFEND take to work?
Voriconazole usually starts to work within 1 to 2 hours, and its effect lasts about 12 hours. How quickly it works can differ from one person to another.
What side effects can VFEND cause?
The common side effects of voriconazole are visual disturbances, nausea, vomiting and rash. Less common ones include elevated liver enzymes, peripheral oedema and headache. Serious but less common side effects include liver damage (hepatotoxicity), photosensitivity and QT prolongation, which need urgent medical attention.
What does VFEND interact with?
Voriconazole can interact with rifampicin, carbamazepine, pimozide and quinidine. Tell your doctor or pharmacist about every medicine you take before you start taking VFEND.
Do I need a prescription to buy VFEND in South Africa?
No, not online: Direct Meds does not ask for a prescription to order VFEND. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Where can I buy VFEND in South Africa?
On Direct Meds: choose the strength and pack, then check out. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →What you will receive
VFEND names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Voriconazole at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.