Vfend
Voriconazole tablets for invasive aspergillosis and systemic candidiasis. It disrupts fungal cell membranes to stop the infection.
- Category
- Antifungals
- Active ingredient
- Voriconazole
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 200mg
Vfend is the reference name. You receive a generic with the same active ingredient and strength.
Supply requirements for Vfend depend on the medicine and destination. The fulfilment partner must confirm them before accepting an order.
Vfend details
- Therapeutic class
- Triazole Antifungal
- Pharmacological class
- Antifungal
- Precautions and warnings
- avoid prolonged sun exposure; monitor liver function; monitor visual function
- Minor side effects
- visual disturbances; nausea; vomiting; rash
- Moderate side effects
- elevated liver enzymes; peripheral oedema; headache
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Supply category
- Prescription-only medicine (POM)
- Originator
- Pfizer
- Onset Time
- 1–2 hours
- Duration
- 12 hours
- Storage instructions
- Store at room temperature.
- Drug interactions
- rifampicin; carbamazepine; pimozide; quinidine
- Age restrictions
- Use with caution in paediatric patients.
Contraindications
hypersensitivity to voriconazole; concurrent use of rifampicin; concurrent use of carbamazepine
Serious side effects
hepatotoxicity, requires immediate medical attention; photosensitivity, requires immediate medical attention; qt prolongation, requires immediate medical attention
Patient summary
Voriconazole tablets for invasive aspergillosis and systemic candidiasis. It disrupts fungal cell membranes to stop the infection.
Mechanism of action
Voriconazole inhibits fungal cytochrome P450-dependent 14-alpha-sterol demethylase, which is vital for fungal ergosterol biosynthesis, effectively disrupting fungal cell membrane formation.
Pregnancy and breastfeeding
Pregnancy: Use is not recommended unless clearly necessary. Breastfeeding: Discontinue breastfeeding during treatment.
What you will receive
Vfend names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Voriconazole at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.