Xarelto
Rivaroxaban tablets for acute coronary syndrome and coronary artery disease. This anticoagulant reduces the risk of blood clots.
All strengths and pack prices
| Strength | Pack | Price | Per unit |
|---|---|---|---|
| 15mg | 28 tablets | $121.00 | $4.32 |
| 15mg | 56 tablets | $167.00 | $2.98 |
- Category
- Blood Thinners
- Active ingredient
- Rivaroxaban
- Route
- Oral use
- Form
- Film-coated tablet; Granules for oral suspension
- Strengths
- 15mg
Xarelto is the reference name. You receive a generic with the same active ingredient and strength.
No prescription needed: we place your order for Xarelto on your behalf.
- Conditions
- Acute Coronary Syndrome · Coronary Artery Disease · Peripheral Artery Disease · Venous Thromboembolism · Deep Vein Thrombosis · Pulmonary Embolism · Atrial Fibrillation
- Therapeutic class
- Antithrombotic agents
- Pharmacological class
- Direct factor Xa inhibitor
- Minor side effects
- haemorrhage; anaemia; dizziness; headache; nausea; constipation; diarrhoea
- Dosage forms
- Film-coated tablet; Granules for oral suspension
- Administration route
- Oral use
- Originator
- Bayer AG
- Storage instructions
- This medicinal product does not require any special storage conditions.
Contraindications
hypersensitivity to rivaroxaban or any excipients; clinically significant active bleeding; lesion or condition at significant risk of major bleeding; concomitant treatment with any other anticoagulant except under specific circumstances; hepatic disease associated with coagulopathy and clinically relevant bleeding risk; pregnancy and breast-feeding
Precautions and warnings
increased risk of bleeding; careful observation for signs of bleeding recommended; not recommended in patients with severe renal impairment unless benefit outweighs risk; caution in patients with moderate renal impairment receiving concomitant medicines that increase rivaroxaban plasma concentrations; caution in patients with an increased bleeding risk; spinal or epidural anaesthesia carries risk of spinal or epidural haematoma; not recommended in patients with prosthetic heart valves; not recommended for acute coronary syndrome patients with prior stroke or transient ischaemic attack; patients should be provided with a patient alert card
Moderate side effects
tachycardia; syncope; pruritus; rash; oedema peripheral; pyrexia; transaminases increased
Serious side effects
intracranial haemorrhage, requires immediate medical attention; gastrointestinal haemorrhage, requires immediate medical attention; retroperitoneal haemorrhage, requires immediate medical attention; spinal or epidural haematoma, requires immediate medical attention; haemorrhagic shock, requires immediate medical attention; anaphylactic reaction, requires immediate medical attention
Patient summary
Rivaroxaban tablets for acute coronary syndrome and coronary artery disease. This anticoagulant reduces the risk of blood clots.
Mechanism of action
Xarelto contains rivaroxaban, a medicine known as a direct oral anticoagulant. It works by blocking a substance in the blood called factor Xa, which is essential for blood clotting. By reducing factor Xa activity, Xarelto helps prevent harmful blood clots from forming in veins and arteries and treats existing clots. It is used to prevent stroke in people with irregular heartbeat (atrial fibrillation), to treat and prevent deep vein clots and lung clots, and to prevent clots after hip or knee replacement surgery.
Drug interactions
other anticoagulants; NSAIDs; acetylsalicylic acid; antiplatelet agents; CYP3A4 and P-gp inhibitors; selective serotonin reuptake inhibitors; serotonin norepinephrine reuptake inhibitors
Age restrictions
Not recommended for children aged less than 18 years except for treatment of VTE and prevention of VTE recurrence in children weighing from 30 kg.
Pregnancy and breastfeeding
Pregnancy: Contraindicated during pregnancy. Animal studies have shown reproductive toxicity. Women of childbearing potential should avoid becoming pregnant during treatment. Breastfeeding: Confirm breastfeeding suitability with a qualified clinician or pharmacist before use.
FAQ
Will I receive the original Xarelto?
No. Xarelto is the original brand, made by Bayer AG, and Direct Meds uses the name to identify the medicine: you receive a generic with the same active ingredient (rivaroxaban) at the same strength. The generic brand and manufacturer depend on available stock.
How much does Xarelto cost in South Africa?
Xarelto comes in a 15mg strength, in packs of 28 to 56 tablets, and the price of every option is shown above. Prices are set in US dollars and converted. Larger packs cost less per tablet.
Payment and prices →What are the brand names for rivaroxaban in South Africa?
In South Africa, rivaroxaban is also sold under brand names such as Rezalto, Rothrom and Xabriva.
What is Xarelto used for?
Xarelto contains rivaroxaban, used for acute coronary syndrome, coronary artery disease, peripheral artery disease, venous thromboembolism and deep vein thrombosis.
What are the side effects of Xarelto?
The common side effects of rivaroxaban are haemorrhage, anaemia, dizziness, headache, nausea and constipation. Less common ones include tachycardia, syncope, itching (pruritus), rash, oedema peripheral and pyrexia. Serious but less common side effects include intracranial haemorrhage, gastrointestinal haemorrhage, retroperitoneal haemorrhage and spinal or epidural haematoma, which need urgent medical attention.
Which medicines interact with Xarelto?
Rivaroxaban can interact with other anticoagulants, NSAIDs, acetylsalicylic acid, antiplatelet agents, CYP3A4 and P-gp inhibitors and selective serotonin reuptake inhibitors. Tell your doctor or pharmacist about every medicine you take before you start taking Xarelto.
Is Xarelto available over the counter in South Africa?
Online, yes: Direct Meds does not ask for a prescription to order Xarelto. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Do you deliver Xarelto to South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →What you will receive
Xarelto names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Rivaroxaban at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.