Aldactone
Spironolactone tablets for high blood pressure and heart failure. Unlike most diuretics, it conserves potassium rather than depleting it.
- Category
- Heart & Blood Pressure
- Active ingredient
- Spironolactone
- Route
- Oral use
- Form
- Tablet
- Strengths
- 25mg · 50mg · 100mg
Aldactone is the reference name. You receive a generic with the same active ingredient and strength.
No prescription needed: we place your order for Aldactone on your behalf.
- Conditions
- Hypertension · Heart Failure · Oedema
- Alternative names
- spironolactone
- Therapeutic class
- Aldosterone Receptor Antagonist
- Pharmacological class
- Potassium-Sparing Diuretic
- Known off-label uses
- acne vulgaris; hirsutism
- Contraindications
- hyperkalaemia; addison's disease; anuria
- Minor side effects
- headache; nausea; dizziness
- Moderate side effects
- gynaecomastia; hyperkalaemia; electrolyte imbalance
- Dosage forms
- Tablet
- Administration route
- Oral use
- Originator
- Pfizer
- Onset Time
- 2–3 days
- Duration
- 24–72 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- ACE Inhibitors; Potassium Supplements; NSAIDs
- Age restrictions
- Approved for paediatric and adult populations.
Serious side effects
severe hyperkalaemia, requires immediate medical attention; anaphylaxis, requires immediate medical attention
Patient summary
Spironolactone tablets for high blood pressure and heart failure. Unlike most diuretics, it conserves potassium rather than depleting it.
Mechanism of action
Antagonises aldosterone receptors in the distal renal tubules, promoting sodium and water excretion while conserving potassium.
Pregnancy and breastfeeding
Pregnancy: Use if potential benefits outweigh risks. Breastfeeding: Confirm breastfeeding suitability with a qualified clinician or pharmacist before use.
Is the Aldactone on Direct Meds a generic?
Yes, you receive a generic. Aldactone is the original brand, made by Pfizer, and Direct Meds uses the name to identify the medicine; the generic has the same active ingredient (spironolactone) at the strength you choose. The generic brand and manufacturer depend on available stock.
How much does Aldactone cost in South Africa?
It depends on the strength and pack. Aldactone comes in 25mg, 50mg and 100mg strengths, in packs of 30 to 360 tablets, and the price of every option is shown above in rand, converted from US dollars. Larger packs cost less per tablet.
Payment and prices →What is Aldactone used for?
Aldactone contains spironolactone, used for hypertension, heart failure and oedema.
How long does Aldactone take to work?
Spironolactone usually starts to work within 2 to 3 days. The exact timing differs between people.
What side effects can Aldactone cause?
The common side effects of spironolactone are headache, nausea and dizziness. Less common ones include gynaecomastia, hyperkalaemia and electrolyte imbalance. Serious but less common side effects include severe hyperkalaemia and anaphylaxis, which need urgent medical attention.
Which medicines interact with Aldactone?
Spironolactone can interact with ACE inhibitors, potassium supplements and NSAIDs. Tell your doctor or pharmacist about every medicine you take before you start taking Aldactone.
Do I need a prescription to buy Aldactone in South Africa?
No, not online: Direct Meds does not ask for a prescription to order Aldactone. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Can I buy Aldactone online in South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →What you will receive
Aldactone names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Spironolactone at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.