Buy Avanafil (Spedra) Online

Avanafil (Spedra) Buyer and Patient Handbook in South Africa

What is Avanafil (Spedra)?

Avanafil (Spedra) is a phosphodiesterase-5 (PDE-5) inhibitor used to treat Erectile Dysfunction in adult men. It belongs to the same class as Sildenafil and Tadalafil but works faster and is cleared more quickly from the body. The medication is approved by the South African Health Products Regulatory Authority (SAHPRA) and is supplied as oral tablets.

Who Should Use Avanafil (Spedra)?

• Men aged 18 years and older with diagnosed erectile dysfunction
• Individuals seeking a fast-acting option (onset ≈ 15 minutes)
• Patients who have not responded well to other PDE-5 inhibitors

How Does It Work?

Avanafil blocks the PDE-5 enzyme, which normally breaks down cyclic guanosine monophosphate (cGMP) in penile tissue. By preserving cGMP, blood vessels relax and blood flow increases during sexual stimulation, enabling an erection. The drug’s rapid onset means it can be taken shortly before planned activity, but it does not cause an erection without sexual arousal. Abuse potential is low; however, it should not be combined with recreational drugs that affect blood pressure.

Why Choose Avanafil (Spedra)?

• Fast onset - effects can be felt within 15 minutes, shorter than many alternatives
• Shorter duration - less risk of prolonged erection (priapism) compared with longer-acting PDE-5 inhibitors
• Fewer food interactions - high-fat meals have minimal impact on absorption

Off-label uses (e.g., pulmonary arterial hypertension) are not approved; discuss any alternative interest with a qualified health professional.

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

• 50 mg tablet - starting dose for most patients
• 100 mg tablet - for those needing stronger effect
• 200 mg tablet - maximum recommended dose

How to Take

1. Swallow the tablet whole with a full glass of water.
2. Take it 15-30 minutes before sexual activity.
3. Do not exceed one tablet in a 24-hour period.

Missed Dose

If a dose is missed, take it as soon as you remember only if there is at least 12 hours until the next planned dose. Otherwise, skip it and resume the regular schedule.

Overdose

In case of suspected overdose, seek emergency medical care immediately. Symptoms may include severe headache, vision changes, or a painful, prolonged erection lasting longer than 4 hours.

Special Populations

• Elderly (≥ 65 years): Start at 50 mg; monitor blood pressure.
• Renal impairment: Use the 50 mg dose; avoid if severe.
• Hepatic impairment: No dose adjustment required for mild disease; avoid in severe liver disease.

Lifestyle & Diet

• Alcohol: Moderate consumption is acceptable; excessive intake can lower effectiveness.
• Grapefruit: No clinically significant interaction, but avoid large quantities if you have liver disease.
• Smoking: May reduce overall response; cessation is advisable.

Precautions and Warnings

• Do not use if you have taken nitrates (e.g., nitroglycerin) within the past 24 hours.
• Caution in patients with uncontrolled hypertension, recent Heart Attack, or severe Heart Failure.
• Avoid if you have a known allergy to avanafil or any tablet excipients.

Drug Interactions

Potential Side Effects

Common Side Effects

• Headache
• Flushing
• Nasal congestion
• Back Pain

Less Common Side Effects

• Dizziness
• Vision disturbance (blue-tinted vision)
• Indigestion

Serious Side Effects

• Painful erection lasting > 4 hours (priapism) - seek urgent care
• Sudden loss of vision or hearing - contact a doctor immediately

Who Should Avoid This Medication?

• Patients using nitrates or nitric-oxide donors
• Individuals with severe uncontrolled hypertension or hypotension
• Men with a History of non-arteritic anterior ischemic optic neuropathy (NAION)

Storage Instructions

• Keep tablets in the original blister pack until use.
• Store at room temperature (15-30 °C); protect from moisture and direct sunlight.
• Keep out of reach of children and pets.

Avanafil (Spedra) Alternatives

Frequently Asked Questions

How quickly can I expect an erection after taking Avanafil (Spedra)?

Most men feel an effect within 15 minutes, though it may take up to 30 minutes for optimal response.

Can I take Avanafil (Spedra) with alcohol?

Moderate alcohol consumption does not usually interfere, but excessive drinking can reduce effectiveness and increase side-effects.

Is it safe to use Avanafil (Spedra) if I have high blood pressure?

If your hypertension is well-controlled and you are not on nitrate therapy, Avanafil is generally safe. Discuss your specific medication list with a health professional.

What should I do if I experience a painful erection lasting more than 4 hours?

Seek emergency medical attention immediately to prevent permanent tissue damage.

Can I take Avanafil (Spedra) daily?

Avanafil is intended for as-needed use; daily dosing is not recommended unless prescribed by a qualified clinician.

Does food affect how Avanafil works?

Unlike some PDE-5 inhibitors, a high-fat meal has minimal impact on absorption, so you may take it with or without food.

Will Avanafil (Spedra) work for women?

The medication is not approved for treating sexual dysfunction in women.

How does Avanafil compare to other erectile-dysfunction pills?

It offers a faster onset and shorter duration than sildenafil and tadalafil, making it suitable for spontaneous activity.

Glossary

• PDE-5 inhibitor: A drug that blocks the enzyme phosphodiesterase-5, enhancing blood flow to the penis.
• cGMP: A chemical messenger that relaxes smooth muscle, allowing erection when sexual stimulation occurs.
• Priapism: A painful, prolonged erection lasting more than 4 hours, which requires urgent treatment.

Disclaimer

The information provided here is for general educational purposes and does not replace professional medical advice. Off-label uses are not endorsed; discuss any alternative applications with a qualified health professional. Users are responsible for their health decisions. Our online pharmacy service offers convenient access to approved medications; all orders are fulfilled in compliance with South African regulations. Always consult a healthcare provider before starting or stopping any medication.