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Famvir (Famciclovir) Buyer and Patient Handbook in South Africa

What is Famvir?

Famvir is an antiviral pill containing the active ingredient famciclovir, used to treat infections caused by herpes viruses. It belongs to the nucleoside analogue class and is approved by the South African Health Products Regulatory Authority (SAHPRA). The medication is available in 250 mg and 500 mg tablet strengths.

Who Should Use Famvir?

• Adults diagnosed with genital herpes, shingles (Herpes Zoster), or oral herpes (Cold Sores).
• Individuals experiencing recurrent outbreaks who need rapid symptom relief.
• Patients for whom a proven oral antiviral is indicated, regardless of gender.

How Does It Work?

Famvir is converted in the body to penciclovir, which mimics viral DNA building blocks and stops the virus from replicating. By halting viral replication, the drug reduces the severity and duration of outbreaks. Do not use if you have a known hypersensitivity to famciclovir or penciclovir.

Why Choose Famvir?

• Proven efficacy: Clinical studies show faster healing compared with placebo.
• Convenient dosing: Only one or two tablets per day, depending on the infection.
• Generic versions of famciclovir provide a lower-cost alternative with the same therapeutic effect.

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

• Genital herpes: 250 mg three times daily for 5-10 days.
• Shingles: 500 mg three times daily for 7 days.
• Cold sores: 250 mg twice daily for 5 days.

How to Take

Swallow the tablet whole with a glass of water; food does not affect absorption, so you may take it with or without meals.

Missed Dose

If you miss a dose, take it as soon as you remember unless it is near the time of the next dose. Do not double-dose.

Overdose

Seek immediate medical attention if you suspect an overdose. Supportive care, such as activated charcoal, may be administered by healthcare professionals.

Special Populations

• Elderly: No dosage adjustment needed, but monitor kidney function.
• Renal impairment: Reduce dose by 50 % if creatinine clearance is <50 ml/min.
• Pregnancy & breastfeeding: Use only if clearly needed; consult a healthcare provider.

Lifestyle & Diet

Avoid excessive alcohol, as it can increase the risk of liver irritation. Grapefruit juice does not affect famciclovir, so it can be consumed safely.

Precautions and Warnings

• Use with caution in patients with a history of kidney disease.
• Inform your provider of any existing medical conditions before starting therapy.
• Discontinue if you develop a rash, itching, or signs of an allergic reaction.

Drug Interactions

Potential Side Effects

Common Side Effects

• Headache
• Nausea
• Fatigue

Less Common Side Effects

• Dizziness
• Diarrhea
• Mild rash

Serious Side Effects

• Severe skin reactions (e.g., Stevens-Johnson syndrome) - seek emergency care
• Kidney problems - report swelling or reduced urine output
• Blood disorders - contact a clinician if you notice unusual bruising or bleeding

Who Should Avoid This Medication?

• Individuals with known hypersensitivity to famciclovir or penciclovir.
• Patients with severe renal impairment (creatinine clearance <30 ml/min) unless dose-adjusted.
• Those currently receiving chemotherapy agents that may interact adversely.

Storage Instructions

• Keep tablets in the original blister pack.
• Store at room temperature (15-30 °C), away from direct sunlight.
• Keep out of reach of children and pets.

Famvir Alternatives

Frequently Asked Questions

How quickly does Famvir start working?

Symptoms usually improve within 2-3 days of starting treatment.

Can I take Famvir with alcohol?

Moderate alcohol is acceptable, but excess may increase liver strain.

Is it safe to use Famvir while breastfeeding?

Small amounts pass into breast milk; discuss risks with your provider.

What should I do if I experience a rash?

Stop the medication and seek medical advice promptly.

Can Famvir prevent future herpes outbreaks?

It reduces outbreak frequency when taken as suppressive therapy, prescribed by a clinician.

How long does a typical shingles course last?

The standard regimen is 7 days of 500 mg three times daily.

Do I need to take Famvir with food?

No, food does not affect absorption; take it with water as convenient.

Will Famvir interfere with my birth control pill?

No known interaction; however, maintain regular contraceptive use.

Glossary

• Antiviral: A drug that inhibits the development of viruses.
• Nucleoside analogue: A compound that mimics natural nucleosides, disrupting viral DNA synthesis.
• Renal clearance: The volume of blood cleared of a substance by the kidneys per minute.

Disclaimer

This handbook provides general information only and does not replace professional medical advice. Off-label use should only be considered after consulting a qualified healthcare provider. Our online service offers educational resources; you remain responsible for any medication decisions. Always discuss your treatment options with a qualified clinician.