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Regaine (Minoxidil) Buyer and Patient Handbook in South Africa

Regaine (Minoxidil) is a topical solution used to treat pattern hair loss in men and women. It belongs to the class of vasodilators and is approved by SAHPRA, the FDA and EMA for over-the-counter use.

What is Regaine?

Regaine is a hair-skin care product that contains the active ingredient minoxidil, a medication that stimulates hair follicles to grow thicker hair. It is available in a plastic bottle with either a 5 % or 10 % strength formulation, suitable for different stages of Alopecia.

Who Should Use Regaine?

• Adults experiencing androgen-type (pattern) hair loss on the scalp.
• Men with vertex or frontal thinning.
• Women with diffuse thinning, particularly on the crown.
• Individuals without a history of hypersensitivity to minoxidil or the product excipients.

How Does It Work?

Minoxidil widens blood vessels around hair follicles, improving blood flow and delivering more oxygen and nutrients. This “fuel boost” prolongs the growth phase (anagen) of the hair cycle, leading to thicker, longer strands. The effect is gradual; most users notice visible improvement after 3-6 months of consistent use.

Why Choose Regaine?

• Brand reliability: Manufactured by a globally recognised company with stringent quality control.
• Convenient strengths: 5 % for most users, 10 % for those needing a stronger response.
• Cost-effective alternatives: Generic minoxidil formulations are bio-equivalent and can reduce out-of-pocket expenses.
• Off-label use: Some clinicians discuss scalp-related conditions such as traction alopecia, but any off-label application should be discussed with a qualified healthcare professional.

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

• 5 % solution: 1 mL applied twice daily (morning and evening).
• 10 % solution: 1 mL applied twice daily; only for adults who have not responded to the 5 % strength.

How to Take

1. Wash and dry the scalp area.
2. Use the dropper to measure 1 mL (≈20 drops).
3. Apply directly to the thinning area and rub gently with fingertips.
4. Allow the solution to dry completely (about 2-4 minutes) before styling or using other hair products.

Missed Dose

If a dose is missed, apply it as soon as you remember unless it is close to the next scheduled dose. In that case, skip the missed dose and continue with the regular schedule; do not double-dose.

Overdose

• Immediate action: Wash the scalp thoroughly with soap and water.
• If systemic symptoms occur (e.g., dizziness, rapid heartbeat), seek emergency medical care or contact the local poison information centre.

Special Populations

• Pregnancy & breastfeeding: Use only if clearly needed and after professional advice.
• Elderly: Start with the 5 % strength; monitor for scalp irritation.
• Children under 18: Not recommended without specialist supervision.

Lifestyle & Diet

• Avoid applying Regaine to irritated, inflamed, or infected skin.
• Do not use hair dyes or harsh chemicals on the same day.
• Grapefruit juice does not affect topical minoxidil, but maintain a balanced diet to support overall hair health.

Precautions and Warnings

• Do not apply to the face, eyes, or broken skin.
• Temporary shedding may occur during the first few weeks; this is a normal sign of follicle cycling.
• Discontinue use if you develop severe scalp irritation, itching, or rash and consult a healthcare professional.

Drug Interactions

Potential Side Effects

Common Side Effects

• Mild scalp itching or dryness
• Flaking or scaling of the scalp
• Temporary increased hair shedding

Less Common Side Effects

• Redness or irritation at the application site
• Unwanted facial hair growth (if product spreads)

Serious Side Effects

• Rapid heart rate or palpitations
• Swelling of hands, feet, or face
• Severe dizziness or fainting - seek medical attention immediately

Who Should Avoid This Medication?

• Individuals allergic to minoxidil or any bottle ingredients.
• Those with active scalp infections (e.g., fungal, bacterial).
• Persons with uncontrolled hypertension without medical supervision.

Storage Instructions

• Keep the bottle tightly closed at room temperature (15-30 °C).
• Store away from direct sunlight and heat sources.
• Keep out of reach of children; the solution is for external use only.

Regaine Alternatives

Frequently Asked Questions

How long does it take to see results?

Most users notice a reduction in hair loss and modest regrowth after 3-4 months, with optimal results at 12 months of continuous use.

Can I use Regaine on a shaved head?

Yes, the solution can be applied to any thinning area, including a shaved scalp, as long as the skin is clean and intact.

Will Regaine stop hair loss permanently?

Regaine maintains existing hair and promotes new growth while it is used. Stopping treatment typically leads to a return of the original pattern of loss within 3-4 months.

Is it safe to use Regaine with other hair products?

Generally safe, but avoid applying other topical agents (e.g., gels, sprays) immediately after Regaine; allow the solution to dry first.

Can I wash my hair after applying Regaine?

Do not wash or rinse the scalp for at least 2 hours after application to allow proper absorption.

Does Regaine work for both men and women?

Yes, the 5 % formulation is approved for both sexes; the 10 % strength is typically reserved for men or women with extensive thinning under professional guidance.

What should I do if I experience severe scalp irritation?

Stop using the product, rinse the area with mild soap and water, and consult a healthcare professional promptly.

Is Regaine compatible with pregnancy?

Use only if a healthcare professional determines the benefits outweigh the risks; otherwise, discontinue during pregnancy.

Glossary

• Anagen phase - The active growth period of a hair follicle.
• Vasodilator - A substance that widens blood vessels, improving blood flow.
• Bio-equivalence - When two products contain the same active ingredient in the same amount and produce the same therapeutic effect.

Disclaimer

The information provided here is for general educational purposes only and does not replace professional medical advice. Off-label uses are mentioned for awareness; any such use should be discussed with a qualified healthcare practitioner. Our online pharmacy platform supplies only registered, quality-assured products; users are responsible for following safe usage guidelines and seeking medical attention when needed.