Buy Zanaflex
zanaflex
$38.40
- Active ingredient: Tizanidine
- Category: Muscle Relaxers
- Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
- Prescription: Included
- Availability: In Stock
Zanaflex contains Tizanidine, which is a centrally acting alpha-2 adrenergic agonist used effectively as a skeletal muscle relaxant. It is indicated for managing spasticity associated with conditions like multiple sclerosis or spinal cord injuries. Zanaflex is beneficial for patients suffering from painful muscle stiffness and spasms who require improved mobility. Tizanidine reduces muscle tone by acting on receptors in the spinal cord to decrease reflex activity. Order Zanaflex 2mg and 4mg tablets online today for prompt delivery within South Africa.
Table of contents
- Zanaflex (Tizanidine) Buyer and Patient Handbook in South Africa
- What is Zanaflex?
- Who Should Use Zanaflex?
- How Does It Work?
- Why Choose Zanaflex?
- Dosage, Administration, Lifestyle and Dietary Recommendations
- Recommended Dosage
- How to Take
- Missed Dose
- Overdose
- Special Populations
- Lifestyle & Diet
- Precautions and Warnings
- Drug Interactions
- Potential Side Effects
- Common Side Effects
- Less Common Side Effects
- Serious Side Effects (seek medical help)
- Who Should Avoid This Medication?
- Storage Instructions
- Zanaflex Alternatives
- Frequently Asked Questions
- How quickly will Zanaflex start working?
- Can I take Zanaflex with my blood-pressure medication?
- Is it safe to drink coffee while on Zanaflex?
- What should I do if I feel unusually sleepy?
- Does Zanaflex cause weight gain?
- Can I use Zanaflex during pregnancy?
- What happens if I miss a dose for several days?
- Is Zanaflex habit-forming?
- Glossary
- Disclaimer
- Zanaflex Properties
- Zanaflex Drug Class
- Zanaflex Connected Conditions
- Related Tags / Keywords
- How to Purchase Zanaflex | Tizanidine Through Our Online Pharmacy
- Reviews
- Write your review
Zanaflex (Tizanidine) Buyer and Patient Handbook in South Africa
What is Zanaflex?
Zanaflex is a centrally-acting muscle relaxant that contains the active ingredient tizanidine, used to relieve muscle spasms caused by conditions such as Multiple Sclerosis or spinal-cord injury. It belongs to the imidazoline-derivative class of drugs and is authorised by the FDA and EMA; it is also registered with South Africa’s Medicines Control Council (MCC). Zanaflex is supplied as oral pill tablets.
Who Should Use Zanaflex?
- Adults with Spasticity from neurological disorders
- Patients experiencing painful muscle tightness that interferes with daily activities
- Individuals who have not responded adequately to non-pharmacologic therapy (physiotherapy, stretching)
How Does It Work?
Zanaflex blocks alpha-2 adrenergic receptors in the spinal cord, which reduces the release of excitatory amino acids and dampens motor-neuron activity. Think of it as turning down the “volume” on an over-active muscle-control circuit, allowing muscles to relax without complete paralysis.
Why Choose Zanaflex?
- Brand confidence: Zanaflex is the reference product with demonstrated bioavailability and consistent quality.
- Rapid onset: Effects are usually felt within 1-2 hours after a dose.
- Convenient dosing: Available in 2 mg and 4 mg tablets, making dose titration simple.
Dosage, Administration, Lifestyle and Dietary Recommendations
Recommended Dosage
- Initial dose: 2 mg taken up to three times daily.
- Maintenance: May be increased to 4 mg per dose, not exceeding 12 mg per day, based on clinical response.
How to Take
- Swallow the tablet whole with a full glass of water.
- Take with food to minimise stomach upset, but avoid taking on an empty stomach.
Missed Dose
- If you remember within 6 hours, take the missed dose.
- Skip it if it is almost time for the next scheduled dose; do not double-dose.
Overdose
- Seek emergency medical help immediately.
- Symptoms may include low blood pressure, slow heart rate, or severe Drowsiness.
Special Populations
| Group | Dose Adjustment | Comments |
|---|---|---|
| Elderly (≥ 65 y) | Start with 2 mg once daily; titrate slowly | Higher risk of hypotension |
| Renal impairment | Reduce dose by 50 % if eGFR < 30 ml/min/1.73 m² | Monitor kidney function |
| Hepatic impairment | Use lowest possible dose; avoid if severe | Liver metabolises tizanidine |
Lifestyle & Diet
- Avoid grapefruit juice - it can raise Zanaflex levels and increase side-effects.
- Alcohol may enhance dizziness; limit consumption.
- Do not operate heavy machinery until you know how the medication affects you.
Precautions and Warnings
- Monitor blood pressure regularly, especially after the first few doses.
- Use caution if you have a history of low blood pressure, heart block, or liver disease.
- Discontinue gradually under medical supervision; abrupt cessation may cause rebound hypertension.
Drug Interactions
| Drug Class | Interaction | Action |
|---|---|---|
| CYP1A2 inhibitors (e.g., fluvoxamine) | ↑ Zanaflex levels | Reduce Zanaflex dose |
| Antihypertensives | Additive hypotension | Monitor BP, adjust therapy |
| CNS depressants (e.g., opioids) | Enhanced drowsiness | Use lowest effective doses |
Potential Side Effects
Common Side Effects
- Dry mouth
- Drowsiness or Fatigue
- Weakness
Less Common Side Effects
- Dizziness
- Nausea
- Elevated liver enzymes
Serious Side Effects (seek medical help)
- Severe hypotension
- Rapid heartbeat (tachycardia)
- Signs of infection (fever, chills)
Who Should Avoid This Medication?
- Known hypersensitivity to tizanidine or any tablet excipients
- Severe liver impairment (Child-Pugh class C)
- Uncontrolled low blood pressure
Storage Instructions
- Keep tablets in the original container, tightly closed.
- Store at room temperature (15 °C-30 °C), away from direct sunlight and moisture.
- Keep out of reach of children.
Zanaflex Alternatives
| Name | Class | Key Difference |
|---|---|---|
| Baclofen | GABA-B agonist | Often used for spinal-cord injury; may cause stiffness |
| Cyclobenzaprine | Tricyclic-type muscle relaxant | Sedation is more pronounced |
| Methocarbamol | Carbamate relaxant | Shorter half-life, less hepatic metabolism |
Frequently Asked Questions
How quickly will Zanaflex start working?
Most patients notice muscle-relaxing effects within 1-2 hours after the first dose.
Can I take Zanaflex with my blood-pressure medication?
Yes, but both drugs can lower blood pressure; your clinician should monitor your readings and may adjust doses.
Is it safe to drink coffee while on Zanaflex?
Moderate coffee intake is not contraindicated, but excessive caffeine can increase heart rate and mask dizziness.
What should I do if I feel unusually sleepy?
Do not drive or operate machinery until the drowsiness passes; discuss dose timing with your clinician.
Does Zanaflex cause weight gain?
Weight change is not a common side effect of Zanaflex.
Can I use Zanaflex during pregnancy?
Tizanidine is classified as Category B3 in South Africa; it should only be used if the potential benefit outweighs the risk.
What happens if I miss a dose for several days?
Contact a healthcare professional before restarting; a gradual titration is recommended to avoid rebound hypertension.
Is Zanaflex habit-forming?
It has a low potential for abuse, but dependence can develop with prolonged high-dose use; follow prescribed limits.
Glossary
- Alpha-2 adrenergic receptor: A protein in the nervous system that helps regulate nerve signal transmission; blocking it reduces Muscle Spasm signals.
- Bioavailability: The proportion of a drug that reaches systemic circulation and can have an active effect.
- Rebound hypertension: A sudden rise in blood pressure that can occur after abrupt discontinuation of certain antihypertensive drugs.
Disclaimer
The information provided here is for general educational purposes only and does not replace professional medical advice. Off-label use of Zanaflex should only be considered after discussion with a qualified healthcare provider. Readers are responsible for ensuring the suitability of any medication for their own health conditions. Our service offers convenient access to licensed pharmacies; all purchases are subject to applicable South African regulations and must be made in compliance with local law. Always consult a qualified clinician before starting or changing any medication regimen.
Zanaflex Properties
- Conditions To Treat: Muscle spasms, multiple sclerosis
- Clinical Use: Muscle relaxant
- Spectrum Of Activity: Alpha-2 agonist
- Mechanism Of Action: Reduces muscle spasticity by blocking nerve impulses
- Length Of Use: Short-term use
- Recommended Dosage: 2-4mg orally every 6-8 hours
- Side Effects: Dizziness, drowsiness, dry mouth
Zanaflex Drug Class
Zanaflex Connected Conditions
Related Tags / Keywords
How to Purchase Zanaflex | Tizanidine Through Our Online Pharmacy
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