Buy Zyloprim Online

Zyloprim (Allopurinol) Buyer and Patient Handbook in South Africa

What is Zyloprim?

Zyloprim is a xanthine oxidase inhibitor used to lower uric acid levels in conditions such as Gout and hyperuricemia. It helps prevent painful flare-ups and chronic joint damage by reducing the formation of uric acid crystals. Zyloprim tablets are approved by the South African Health Products Regulatory Authority (SAHPRA) and are available in 100 mg and 300 mg strengths.

Who Should Use Zyloprim?

• Adults diagnosed with gout or chronic hyperuricemia
• Patients with high uric acid due to chemotherapy or tumour lysis syndrome
• Individuals who have not responded adequately to lifestyle measures (diet, hydration)
• People with a confirmed need for long-term uric acid reduction

How Does It Work?

Allopurinol, the active ingredient in Zyloprim, blocks the enzyme xanthine oxidase, which is responsible for converting purines into uric acid. By inhibiting this step, the drug reduces the amount of uric acid produced, allowing the body to eliminate existing uric acid more efficiently. This mechanism helps prevent crystal deposition in joints, thereby reducing Pain and inflammation.

Why Choose Zyloprim?

• Proven efficacy for long-term control of uric acid levels
• Available in a convenient pill form that can be taken once daily in most cases
• Generic alternatives containing allopurinol are bio-equivalent and often more affordable, while Zyloprim offers a recognized brand reputation for quality

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

*Dose adjustments are made by a health professional based on uric acid levels and renal function.

How to Take

• Swallow the tablet whole with a full glass of water.
• Take Zyloprim with food to reduce stomach irritation.
• Do not crush or chew the tablet.

Missed Dose

If you miss a dose, take it as soon as you remember unless it is close to the time of your next scheduled dose. In that case, skip the missed dose and continue with your regular schedule. Do not double-dose.

Overdose

Signs of overdose may include severe nausea, vomiting, and dizziness. Seek immediate medical attention or call emergency services if an overdose is suspected.

Special Populations

• Elderly: Start with the lowest dose (100 mg) and monitor renal function.
• Renal impairment: Dose reduction is required; follow local guidelines.
• Children: Use is limited; pediatric dosing should be determined by a specialist.

Lifestyle & Diet

• Hydration: Drink plenty of water to aid uric acid excretion.
• Diet: Limit high-purine foods (red meat, organ meats, seafood) and avoid excessive alcohol, especially beer.
• Grapefruit: No known interaction, but maintain a balanced diet.

Precautions and Warnings

• Perform baseline renal and liver function tests before starting therapy.
• Monitor serum uric acid levels after 2-4 weeks, then periodically.
• Increase in gout attacks may occur during the first weeks of treatment; prophylactic low-dose Colchicine or NSAIDs are often recommended.
• Do not use if you have a known hypersensitivity to allopurinol or any component of the tablet.

Drug Interactions

Potential Side Effects

Common Side Effects

• Skin rash
• Mild nausea or upset stomach
• Diarrhoea

Less Common Side Effects

• Elevated liver enzymes
• Itching or hives

Serious Side Effects

• Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) - seek urgent medical care
• Blood disorders (agranulocytosis, aplastic anaemia) - contact a health professional immediately

Who Should Avoid This Medication?

• Patients with a history of severe allergic reaction to allopurinol
• Individuals with active severe liver disease
• Patients currently receiving high-dose Azathioprine without dose adjustment

Storage Instructions

• Keep the tablets in the original container, tightly closed.
• Store at room temperature (15-30 °C), away from moisture and direct sunlight.
• Keep out of reach of children and pets.

Zyloprim Alternatives

Frequently Asked Questions

How long does it take for Zyloprim to lower uric acid levels?

Typically, a measurable reduction is seen within 2-4 weeks, with optimal control often reached after 3-6 months of consistent therapy.

Can I drink alcohol while taking Zyloprim?

Alcohol, especially beer, can raise uric acid levels and increase gout risk. Limit intake and discuss any consumption with your health professional.

Do I need to take any other medication when I start Zyloprim?

A short course of a low-dose colchicine or an NSAID is often prescribed to prevent gout flares during the initial treatment phase.

Is it safe to take Zyloprim during pregnancy?

Allopurinol is classified as Category B3 in South Africa; it should only be used if the potential benefit justifies the potential risk to the fetus. Consult your health professional.

Can Zyloprim be used in children?

Allopurinol is occasionally prescribed for pediatric gout or tumour-lysis syndrome, but dosing must be individualized by a specialist.

What should I do if I develop a rash?

Stop the medication immediately and seek medical attention, as skin reactions can progress to serious conditions.

Does Zyloprim affect blood sugar levels?

Allopurinol does not have a direct impact on glucose metabolism, but any new medication should be monitored if you have Diabetes.

How often should my blood tests be repeated?

Initial renal and liver function tests are done before starting therapy, followed by repeat testing after 2-4 weeks, then every 3-6 months or as advised.

Glossary

• Uric acid: A waste product formed from the breakdown of purines; high levels can form crystals in joints.
• Xanthine oxidase: An enzyme that converts purines into uric acid; the primary target of allopurinol.
• Hyperuricemia: Elevated blood uric acid concentration, often a precursor to gout.

Disclaimer

The information provided here is for general educational purposes only and does not replace professional medical advice. Zyloprim should be used only under the guidance of a qualified health professional. Off-label use requires careful consideration and consultation. Our online pharmacy platform offers convenient access to approved medications, but the final decision and responsibility for treatment lie with the patient and their health care provider.