Chronic Myeloid Leukaemia
Chronic myeloid leukaemia (CML) is a slowly developing cancer of white blood cells that begins in blood stem cells within the bone marrow. It often causes no symptoms early on and may be found by chance on a routine blood test.
Key points
- More than 95 percent of people with CML carry the Philadelphia chromosome, a genetic change that produces an abnormal protein driving disordered white blood cell growth.
- CML progresses through three phases: chronic, accelerated, and blast, and most people are diagnosed while still in the chronic phase.
- For most people, CML can be well controlled for as long as treatment continues, and most people with CML have a normal life expectancy.
Medicines listed for Chronic Myeloid Leukaemia
The listed products for chronic myeloid leukaemia span two broad medicine classes. Imatinib and dasatinib are tyrosine kinase inhibitors, a group that targets the abnormal protein produced by the Philadelphia chromosome. Hydroxycarbamide is a cytostatic agent that reduces the number of abnormal white blood cells in the blood and bone marrow. Gleevec and Hydrea are supplied as tablets; Sprycel comes in a bottle.
Further reading
What is chronic myeloid leukaemia?
Chronic myeloid leukaemia is a slowly developing cancer of white blood cells that begins in blood stem cells within the bone marrow. It often causes no symptoms early on and may be found by chance on a routine blood test.
What are the symptoms of chronic myeloid leukaemia?
Chronic myeloid leukaemia often causes no symptoms early on, so it may be found by chance on a routine blood test.
Which medicines for chronic myeloid leukaemia does Direct Meds sell?
The medicines listed for chronic myeloid leukaemia include products containing hydroxycarbamide, imatinib and dasatinib. Examples include Hydrea and Gleevec.
Can I buy medicines for chronic myeloid leukaemia over the counter in South Africa?
Yes, online. Direct Meds does not ask for a prescription to order medicines for chronic myeloid leukaemia. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Can I order medicines for chronic myeloid leukaemia online in South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →

