Imatinib
Gleevec is the brand-name version of imatinib and the only product on this shelf, a 400 mg tablet used to treat Chronic Myeloid Leukaemia and Gastrointestinal Stromal Tumours.
Medicine containing Imatinib
Key points
- Imatinib is a kinase inhibitor that blocks the BCR-ABL protein in leukaemia cells and c-kit in stromal tumours, slowing or stopping their growth.
- Do not become pregnant while taking imatinib and for 14 days after the final dose; the medicine can harm a developing baby.
- Avoid grapefruit and grapefruit juice during treatment, as they can raise imatinib levels in the blood.
How does Imatinib work?
Imatinib blocks specific enzymes called tyrosine kinases, which act as growth signals inside cells. In chronic myeloid leukaemia, it targets the BCR-ABL protein, a faulty signal that keeps white blood cells dividing without control. In gastrointestinal stromal tumours, it inhibits c-kit, a receptor that drives abnormal growth in the stomach and intestinal wall. By sitting in the enzyme’s active site, imatinib switches off the signal and triggers the cell’s own death programme. It sits within the Oncology Support range as a targeted therapy.
Further reading
FAQ
Which imatinib products does Direct Meds sell?
On Direct Meds, imatinib comes as Gleevec. Compare their forms, strengths and packs.
What are the brand names for imatinib in South Africa?
In South Africa it is also sold as Nuvitab. Names differ from country to country, so the active ingredient is the surest way to compare products.
How much does imatinib cost in South Africa?
Compare the price of each product, strength and pack above. Prices are set in US dollars and converted. Larger packs usually cost less per tablet.
Payment and prices →Is imatinib available over the counter in South Africa?
Yes, online. Direct Meds does not ask for a prescription to order imatinib. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Do you deliver imatinib to South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →Last updated