Dorzolamide
Cosopt pairs 2% dorzolamide with 0.5% timolol in eye drops to lower pressure in Open-angle Glaucoma and Ocular Hypertension. It is the only dorzolamide product listed.
Medicine containing Dorzolamide
Key points
- Dorzolamide is a sulfonamide, and although it is applied to the eye, it is absorbed into the body, so severe sulfonamide reactions including Stevens-Johnson syndrome can occur, though rarely.
- Dorzolamide and its metabolite are cleared mainly by the kidneys, so the drops are not recommended for people with severe kidney impairment.
- Cosopt is indicated for people whose eye pressure is not adequately controlled by a beta-blocker alone.
How does Dorzolamide work?
Dorzolamide hydrochloride blocks an enzyme called carbonic anhydrase II in the ciliary body, the part of the eye that produces its internal fluid. With less of that enzyme working, the eye makes less fluid, and the pressure inside drops.
Elevated pressure inside the eye is the main risk factor for optic nerve damage and the loss of side vision in glaucoma. In the Eye Care range, the two active ingredients in Cosopt lower that pressure through separate pathways.
Further reading
FAQ
Which dorzolamide products does Direct Meds sell?
On Direct Meds, dorzolamide comes as Cosopt. Compare their forms, strengths and packs.
How is dorzolamide priced?
Compare the price of each product, strength and pack above. Prices are set in US dollars and converted.
Payment and prices →Do I need a prescription for dorzolamide in South Africa?
No, not online. Direct Meds does not ask for a prescription to order dorzolamide. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Do you deliver dorzolamide to South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →Last updated