Duloxetine
Duloxetine, sold as Cymbalta, is an antidepressant used for depression and nerve pain. One product sits on this shelf, in four strengths from 20 mg to 60 mg capsules.
Medicine containing Duloxetine
Key points
- Duloxetine is a serotonin-noradrenaline reuptake inhibitor (SNRI), acting on two brain chemicals at once.
- It is listed for Major Depressive Disorder, diabetic nerve pain, and fibromyalgia.
- Do not combine duloxetine with St John’s wort or MAOI antidepressants such as moclobemide; the interaction can trigger serotonin syndrome, marked by fast heartbeat, shaking, and confusion.
How does Duloxetine work?
Duloxetine blocks the reabsorption of serotonin and noradrenaline into nerve cells, raising the levels of both in the brain. More serotonin can ease low mood and anxiety; more noradrenaline can quiet the pain signals that damaged nerves send to the brain. This dual action is why duloxetine sits in the Antidepressants category yet is also used for Diabetic Peripheral Neuropathic Pain.
Further reading
FAQ
In which products can I find duloxetine?
On Direct Meds, duloxetine comes as Cymbalta. Compare their forms, strengths and packs.
Which brands contain duloxetine?
In South Africa it is also sold as Cymgen, Yelate and Deotin. Names differ from country to country, so the active ingredient is the surest way to compare products.
How is duloxetine priced?
Compare the price of each product, strength and pack above. Prices are set in US dollars and converted.
Payment and prices →Do I need a prescription for duloxetine in South Africa?
No, not online. Direct Meds does not ask for a prescription to order duloxetine. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Where can I buy duloxetine in South Africa?
On Direct Meds: choose the product, strength and pack, then check out. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →Last updated