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Cymbalta

Cymbalta

Duloxetine

Duloxetine capsules for depression and diabetic nerve pain. The coating stops the medicine releasing in the stomach.

All strengths and pack prices
StrengthPackPricePer unit
20mg30 capsules$70.00$2.33
20mg60 capsules$99.00$1.65
20mg90 capsules$125.00$1.39
20mg120 capsules$154.00$1.28
20mg180 capsules$210.00$1.17
20mg270 capsules$295.00$1.09
20mg360 capsules$377.00$1.05
30mg30 capsules$84.00$2.80
30mg60 capsules$119.00$1.98
30mg90 capsules$154.00$1.71
30mg120 capsules$188.00$1.57
30mg180 capsules$258.00$1.43
30mg270 capsules$362.00$1.34
40mg30 capsules$88.00$2.93
40mg60 capsules$125.00$2.08
40mg90 capsules$162.00$1.80
40mg120 capsules$200.00$1.67
40mg180 capsules$275.00$1.53
40mg270 capsules$390.00$1.44
60mg30 capsules$82.00$2.73
60mg60 capsules$128.00$2.13
60mg90 capsules$175.00$1.94
60mg120 capsules$221.00$1.84
60mg180 capsules$314.00$1.74
60mg270 capsules$454.00$1.68
Active ingredient
Duloxetine
Route
Oral use
Form
Gastro-resistant capsule, hard
Strengths
20mg · 30mg · 40mg · 60mg

Cymbalta is the reference name. You receive a generic with the same active ingredient and strength.

No prescription needed: we place your order for Cymbalta on your behalf.

Alternative names
duloxetine
Therapeutic class
Serotonin-Norepinephrine Reuptake Inhibitor (SNRI)
Pharmacological class
Antidepressant
Known off-label uses
stress urinary incontinence
Minor side effects
nausea; dry mouth; somnolence
Moderate side effects
decreased appetite; insomnia; fatigue
Dosage forms
Gastro-resistant capsule, hard
Administration route
Oral use
Originator
Eli Lilly
Onset time
1–4 weeks
Duration
24 hours
Storage instructions
Store below 25°C.
Drug interactions
MAO Inhibitors; Fluoxetine; Alcohol
Age restrictions
Approved for paediatric patients over seven years and adults.
Contraindications

concurrent MAO inhibitor use; uncontrolled narrow-angle glaucoma; severe hepatic impairment

Serious side effects

suicidal ideation, requires immediate medical attention; serotonin syndrome, requires immediate medical attention

Patient summary

Duloxetine capsules for depression and diabetic nerve pain. The coating stops the medicine releasing in the stomach.

Mechanism of action

Inhibits synaptic reuptake of both serotonin and norepinephrine in central pain-regulatory and mood control structures.

Pregnancy and breastfeeding

Pregnancy: Risk of neonatal behavioural syndrome. Breastfeeding: Consult a clinician.

FAQ

Will I receive the original Cymbalta?

No. Cymbalta is the original brand, made by Eli Lilly, and Direct Meds uses the name to identify the medicine: you receive a generic with the same active ingredient (duloxetine) at the strength you choose. The generic brand and manufacturer depend on available stock.

How much does Cymbalta cost in South Africa?

The price varies with strength and pack size. Cymbalta comes in 20mg, 30mg, 40mg and 60mg strengths, in packs of 30 to 360 capsules, and the price of every option is shown above. Prices are set in US dollars and converted. Larger packs cost less per capsule.

Payment and prices →

Is Cymbalta sold under other names?

In South Africa, duloxetine is also sold under brand names such as Cymgen, Yelate and Deotin.

What is Cymbalta used for?

Cymbalta contains duloxetine, used for major depressive disorder, diabetic peripheral neuropathic pain and fibromyalgia.

When does Cymbalta start working?

Duloxetine usually starts to work within 1 to 4 weeks. The exact timing differs between people.

What side effects can Cymbalta cause?

The common side effects of duloxetine are nausea, dry mouth and drowsiness (somnolence). Less common ones include decreased appetite, insomnia and fatigue. Serious but less common side effects include suicidal ideation and serotonin syndrome, which need urgent medical attention.

Does Cymbalta interact with alcohol?

Alcohol can interact with duloxetine, so check with a doctor or pharmacist before you drink while taking Cymbalta.

Which medicines interact with Cymbalta?

Duloxetine can interact with MAO inhibitors and fluoxetine. Tell your doctor or pharmacist about every medicine you take before you start taking Cymbalta.

Do I need a prescription to buy Cymbalta in South Africa?

No, not online: Direct Meds does not ask for a prescription to order Cymbalta. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.

Ordering without a prescription →

Where can I buy Cymbalta in South Africa?

On Direct Meds: choose the strength and pack, then check out. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.

How ordering works →

What you will receive

Cymbalta names the medicine you are looking for. What ships is a generic version of it.

  • A generic containing Duloxetine at the strength you pick.
  • Which generic brand and maker ships depends on stock and destination.
  • Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.

How we compare medicine brands and generics