Dydrogesterone
Duphaston is the 10 mg tablet form of dydrogesterone, a synthetic progestin that mimics the body’s own progesterone to regulate the womb lining. It is listed for Progesterone Deficiency, Endometriosis and threatened miscarriage.
Medicine containing Dydrogesterone
Key points
- Progestins as a class carry a well-established risk of liver injury, though reported cases are rare, self-limiting, and resolve when the medicine is stopped.
- Common side effects include nausea, headaches, anxiety, weight gain and breast tenderness.
How does Dydrogesterone work?
Dydrogesterone acts on the same hormonal pathways as natural progesterone, triggering the signals that thicken and stabilise the endometrium (the womb lining) after ovulation. Without enough progesterone, that lining breaks down unevenly, causing irregular bleeding or making it harder for a fertilised egg to implant. Dydrogesterone fills that gap, supporting the lining through the second half of the cycle.
In the Women’s Health range, Duphaston is the brand-name product for this molecule, supplied as a 10 mg tablet.
Further reading
FAQ
Which dydrogesterone products does Direct Meds sell?
On Direct Meds, dydrogesterone comes as Duphaston. Compare their forms, strengths and packs.
How is dydrogesterone priced?
Compare the price of each product, strength and pack above. Prices are set in US dollars and converted. Larger packs usually cost less per tablet.
Payment and prices →Is dydrogesterone available over the counter in South Africa?
Yes, online. Direct Meds does not ask for a prescription to order dydrogesterone. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Do you deliver dydrogesterone to South Africa?
Yes. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →Last updated