Duphaston
Dydrogesterone tablets for progesterone deficiency and endometriosis. It mimics the body's own progesterone to regulate the womb lining.
- Categories
- Women's Health · Menopause & HRT
- Active ingredient
- Dydrogesterone
- Route
- Oral use
- Form
- Tablet
- Strengths
- 10mg
Duphaston is the reference name. You receive a generic with the same active ingredient and strength.
No prescription needed: we place your order for Duphaston on your behalf.
- Conditions
- Progesterone Deficiency · Endometriosis · Threatened Miscarriage
- Alternative names
- dydrogesterone
- Therapeutic class
- Synthetic Progestogen
- Pharmacological class
- Progesterone Derivative
- Minor side effects
- breakthrough bleeding; headache; nausea
- Moderate side effects
- breast tenderness; weight changes; mood swing
- Serious side effects
- deep vein thrombosis, requires immediate medical attention
- Dosage forms
- Tablet
- Administration route
- Oral use
- Originator
- Abbott
- Onset Time
- 24–48 hours
- Duration
- 24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Rifampin; Phenytoin
- Age restrictions
- Approved for adult females.
Contraindications
unexplained vaginal bleeding; active thromboembolic disease; known sex hormone-dependent neoplasms
Patient summary
Dydrogesterone tablets for progesterone deficiency and endometriosis. It mimics the body's own progesterone to regulate the womb lining.
Mechanism of action
Replaces missing progesterone in target tissues, transforming proliferative endometrium into secretory phases to stabilise uterine structures.
Pregnancy and breastfeeding
Pregnancy: Widely used for threatened miscarriage. Breastfeeding: Consult a doctor.
Is the Duphaston on Direct Meds a generic?
Yes, you receive a generic. Duphaston is the original brand, made by Abbott, and Direct Meds uses the name to identify the medicine; the generic has the same active ingredient (dydrogesterone) at the same strength. The generic brand and manufacturer depend on available stock.
What is the price of Duphaston in rand?
Duphaston comes in a 10mg strength, in packs of 20 to 360 tablets, and the price of every option is shown above in rand, converted from US dollars. Larger packs cost less per tablet.
Payment and prices →What is Duphaston used for?
Duphaston contains dydrogesterone, used for progesterone deficiency, endometriosis and threatened miscarriage.
When does Duphaston start working?
Dydrogesterone usually starts to work within 24 to 48 hours, and its effect lasts about 24 hours. This varies from person to person.
What are the side effects of Duphaston?
The common side effects of dydrogesterone are breakthrough bleeding, headache and nausea. Less common ones include breast tenderness, weight changes and mood swings. Serious but less common side effects include deep vein thrombosis, which needs urgent medical attention.
Which medicines interact with Duphaston?
Dydrogesterone can interact with rifampicin and phenytoin. Tell your doctor or pharmacist about every medicine you take before you start taking Duphaston.
Can I buy Duphaston over the counter in South Africa?
Online, yes: Direct Meds does not ask for a prescription to order Duphaston. We are a broker, not a dispensing pharmacy. We arrange orders and delivery with our affiliated supplier on your behalf.
Ordering without a prescription →Where can I buy Duphaston in South Africa?
On Direct Meds: choose the strength and pack, then check out. Our affiliated supplier delivers across South Africa. Estimated delivery is 7 days with Express Delivery, which includes online tracking, or up to 3 weeks with Regular Delivery.
How ordering works →What you will receive
Duphaston names the medicine you are looking for. What ships is a generic version of it.
- A generic containing Dydrogesterone at the strength you pick.
- Which generic brand and maker ships depends on stock and destination.
- Check the active ingredient, strength, form, pack, seal, batch and expiry when it arrives.